On-chip fluorescence sensing for fluidics platforms using thin film silicon photodetectors

Journal Article (Journal Article)

The integration of fluorescence sensing directly into the fluidic channel in lab-on-a chip systems using thin film Si detectors enables on-chip multi-target medical diagnostics and biochemical analyses. This paper reports on the experimental demonstration and theoretical analysis of a filter-free thin film fluorescence sensor designed for integration into the channel of a fluidic platform. Static tests of this optical sensor show repeatable detection of 6-Hex fluorophore concentrations from 300 nM to 20 µM, with an average signal-to-noise ratio of 26 dB-50 dB, which agrees well with the theoretical model.

Full Text

Duke Authors

Cited Authors

  • Dighe, A; Jokerst, N

Published Date

  • January 1, 2020

Published In

Volume / Issue

  • 11 / 10

Start / End Page

  • 5772 - 5782

Electronic International Standard Serial Number (EISSN)

  • 2156-7085

Digital Object Identifier (DOI)

  • 10.1364/BOE.402246

Citation Source

  • Scopus