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Advancing Toward 3D Printing of Bioresorbable Shape Memory Polymer Stents.

Publication ,  Journal Article
Yeazel, TR; Becker, ML
Published in: Biomacromolecules
October 2020

Stents have evolved significantly since their introduction to the medical field in the early 1980s, becoming widely used in percutaneous coronary interventions and following nephrological procedures. However, the current commercially available stents do not degrade and remain in the body forever, leading to problems like restenosis in cardiovascular applications or requiring removal procedures in ureteral applications. Efforts to replace metal with resorbable materials have largely been halted after the commercial failure of and safety concerns elicited by Abbott's Absorb stent in 2017. Industry continues to use common polymers such as poly(l-lactide) (PLLA) and polycaprolactone (PCL) for biomedical products, but due to the weak mechanical properties of these bioresorbable materials in comparison to metals, these devices have struggled to accomplish the goals set, increasing risk of thrombosis. 3D printing stents using bioresorbable and shape memory materials could provide a method of patient-personalized production, remove the need for balloon expansion, and limit stent migration, thus bringing a new age of stent technology. The investigation of a range of 3D-printable and bioresorbable shape-memory polymers can provide solutions to the shortcomings of previously explored bioresorbable stents and revitalize the medical device industry efforts into advancing stent technology.

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Published In

Biomacromolecules

DOI

EISSN

1526-4602

ISSN

1525-7797

Publication Date

October 2020

Volume

21

Issue

10

Start / End Page

3957 / 3965

Related Subject Headings

  • Stents
  • Smart Materials
  • Prosthesis Design
  • Printing, Three-Dimensional
  • Polymers
  • Percutaneous Coronary Intervention
  • Humans
  • Absorbable Implants
  • 40 Engineering
  • 34 Chemical sciences
 

Citation

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Yeazel, T. R., & Becker, M. L. (2020). Advancing Toward 3D Printing of Bioresorbable Shape Memory Polymer Stents. Biomacromolecules, 21(10), 3957–3965. https://doi.org/10.1021/acs.biomac.0c01082
Yeazel, Taylor R., and Matthew L. Becker. “Advancing Toward 3D Printing of Bioresorbable Shape Memory Polymer Stents.Biomacromolecules 21, no. 10 (October 2020): 3957–65. https://doi.org/10.1021/acs.biomac.0c01082.
Yeazel TR, Becker ML. Advancing Toward 3D Printing of Bioresorbable Shape Memory Polymer Stents. Biomacromolecules. 2020 Oct;21(10):3957–65.
Yeazel, Taylor R., and Matthew L. Becker. “Advancing Toward 3D Printing of Bioresorbable Shape Memory Polymer Stents.Biomacromolecules, vol. 21, no. 10, Oct. 2020, pp. 3957–65. Epmc, doi:10.1021/acs.biomac.0c01082.
Yeazel TR, Becker ML. Advancing Toward 3D Printing of Bioresorbable Shape Memory Polymer Stents. Biomacromolecules. 2020 Oct;21(10):3957–3965.
Journal cover image

Published In

Biomacromolecules

DOI

EISSN

1526-4602

ISSN

1525-7797

Publication Date

October 2020

Volume

21

Issue

10

Start / End Page

3957 / 3965

Related Subject Headings

  • Stents
  • Smart Materials
  • Prosthesis Design
  • Printing, Three-Dimensional
  • Polymers
  • Percutaneous Coronary Intervention
  • Humans
  • Absorbable Implants
  • 40 Engineering
  • 34 Chemical sciences