Pathophysiology and Pathology of Acute Kidney Injury in Patients With COVID-19.

Journal Article (Journal Article;Review)

Acute kidney injury (AKI) is common among hospitalized patients with Coronavirus Infectious Disease 2019 (COVID-19), with the occurrence of AKI ranging from 0.5% to 80%. The variability in the occurrence of AKI has been attributed to the difference in geographic locations, race/ethnicity, and severity of illness. AKI among hospitalized patients is associated with increased length of stay and in-hospital deaths. Even patients with AKI who survive to hospital discharge are at risk of developing chronic kidney disease or end-stage kidney disease. An improved knowledge of the pathophysiology of AKI in COVID-19 is crucial to mitigate and manage AKI and to improve the survival of patients who developed AKI during COVID-19. The goal of this article is to provide our current understanding of the etiology and the pathophysiology of AKI in the setting of COVID-19.

Full Text

Duke Authors

Cited Authors

  • Ng, JH; Bijol, V; Sparks, MA; Sise, ME; Izzedine, H; Jhaveri, KD

Published Date

  • September 2020

Published In

Volume / Issue

  • 27 / 5

Start / End Page

  • 365 - 376

PubMed ID

  • 33308501

Pubmed Central ID

  • PMC7574722

Electronic International Standard Serial Number (EISSN)

  • 1548-5609

Digital Object Identifier (DOI)

  • 10.1053/j.ackd.2020.09.003


  • eng

Conference Location

  • United States