Infection control and other stewardship strategies in late onset sepsis, necrotizing enterocolitis, and localized infection in the neonatal intensive care unit.

Journal Article (Journal Article)

Suspected or proven late onset sepsis, necrotizing enterocolitis, urinary tract infections, and ventilator associated pneumonia occurring after the first postnatal days contribute significantly to the total antibiotic exposures in neonatal intensive care units. The variability in definitions and diagnostic criteria in these conditions lead to unnecessary antibiotic use. The length of treatment and choice of antimicrobial agents for presumed and proven episodes also vary among centers due to a lack of supportive evidence and guidelines. Implementation of robust antibiotic stewardship programs can encourage compliance with appropriate dosages and narrow-spectrum regimens.

Full Text

Duke Authors

Cited Authors

  • Aleem, S; Wohlfarth, M; Cotten, CM; Greenberg, RG

Published Date

  • December 2020

Published In

Volume / Issue

  • 44 / 8

Start / End Page

  • 151326 -

PubMed ID

  • 33158599

Pubmed Central ID

  • PMC7550069

Electronic International Standard Serial Number (EISSN)

  • 1558-075X

Digital Object Identifier (DOI)

  • 10.1016/j.semperi.2020.151326


  • eng

Conference Location

  • United States