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Interventions to Improve Adherence to Cardiovascular Medication: What About Gender Differences? A Systematic Literature Review.

Publication ,  Journal Article
Vervloet, M; Korevaar, JC; Leemrijse, CJ; Paget, J; Zullig, LL; van Dijk, L
Published in: Patient Prefer Adherence
2020

BACKGROUND: Compared to men, women have lower treatment rates for cardiovascular disease (CVD), are at higher risk for medication non-adherence and have different reasons for being non-adherent. The aim of this study was to synthesize and evaluate gender-specific adherence-promoting interventions for cardiovascular medication and gender-specific effects of gender-neutral interventions. METHODS: A systematic literature search was performed in PubMed, Embase, PsycINFO, CINAHL and Cochrane Library from January 2007 to October 2019. Intervention studies (with control group) aimed at improving cardiovascular medication adherence with minimally 14 weeks follow-up were included. Two reviewers independently screened titles and abstracts. Full text was obtained for selected abstracts and screened for final inclusion. Data extraction included gender-specific targeting or analysis. RESULTS: The search identified 6502 citations. After screening title and abstract, full text was obtained from 127 potentially eligible articles. Ultimately, 11 articles were included that analyzed gender differences in gender-neutral interventions. Two reported a gender-specific intervention effect. Using an electronic reminder device, one study increased statin adherence in women. The other found a larger increase in adherence to CVD medication following telephone counseling for men than women. Nine studies did not identify a gender-specific effect. CONCLUSION: Despite differences in levels of and reasons for non-adherence, most studies addressing adherence did not analyze potential differences in effect by gender. Moreover, none of the identified studies used gender-specific adherence promoting interventions. Increasing awareness about gender differences in adherence might lead to better tailoring of interventions to gender-specific needs and better results in improving adherence.

Duke Scholars

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Published In

Patient Prefer Adherence

DOI

ISSN

1177-889X

Publication Date

2020

Volume

14

Start / End Page

2055 / 2070

Location

New Zealand

Related Subject Headings

  • 4203 Health services and systems
  • 1103 Clinical Sciences
 

Citation

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Vervloet, M., Korevaar, J. C., Leemrijse, C. J., Paget, J., Zullig, L. L., & van Dijk, L. (2020). Interventions to Improve Adherence to Cardiovascular Medication: What About Gender Differences? A Systematic Literature Review. Patient Prefer Adherence, 14, 2055–2070. https://doi.org/10.2147/PPA.S260562
Vervloet, Marcia, Joke C. Korevaar, Chantal J. Leemrijse, John Paget, Leah L. Zullig, and Liset van Dijk. “Interventions to Improve Adherence to Cardiovascular Medication: What About Gender Differences? A Systematic Literature Review.Patient Prefer Adherence 14 (2020): 2055–70. https://doi.org/10.2147/PPA.S260562.
Vervloet M, Korevaar JC, Leemrijse CJ, Paget J, Zullig LL, van Dijk L. Interventions to Improve Adherence to Cardiovascular Medication: What About Gender Differences? A Systematic Literature Review. Patient Prefer Adherence. 2020;14:2055–70.
Vervloet, Marcia, et al. “Interventions to Improve Adherence to Cardiovascular Medication: What About Gender Differences? A Systematic Literature Review.Patient Prefer Adherence, vol. 14, 2020, pp. 2055–70. Pubmed, doi:10.2147/PPA.S260562.
Vervloet M, Korevaar JC, Leemrijse CJ, Paget J, Zullig LL, van Dijk L. Interventions to Improve Adherence to Cardiovascular Medication: What About Gender Differences? A Systematic Literature Review. Patient Prefer Adherence. 2020;14:2055–2070.

Published In

Patient Prefer Adherence

DOI

ISSN

1177-889X

Publication Date

2020

Volume

14

Start / End Page

2055 / 2070

Location

New Zealand

Related Subject Headings

  • 4203 Health services and systems
  • 1103 Clinical Sciences