Cognitive and motor function in adults with spina bifida myelomeningocele: a pilot study.

Journal Article (Journal Article)

PURPOSE: Determine the feasibility and utility of using a battery of tests utilized, so far, to assess neurological-cognitive functions in the typical adult population and identify the spectrum of these functions in adult SBM patients. METHODS: Prospective study in which 15 participants (mean age = 28.7 ± 8.7 years, range = 19-45 years) completed the targeted battery of tests (n = 5-15/test) previously standardized to the general population. Results were compared with normative data. RESULTS: Statistically significant differences with normative means were noted in the following tests: Montreal Cognitive Assessment (MoCA), Functional Activities Questionnaire (FAQ), and NIH Toolbox Fine Motor (Dexterity and Grip Strength) tests. Cohort means for NIH Toolbox Fluid, Crystallized, and Cognitive Composite Scores and Timed Up and GO (TUG) were not different from normative means. CONCLUSION: All tests were successfully completed by cohort. Whereas many aspects of cognition were normal, tests assessing visual-constructural, calculation, motor, and fluency functions did show differences from population means. Numerous tests assessing multiple domains are needed and can be used in future aging studies to appreciate the spectrum of cognitive and motor abilities in adults with SBM.

Full Text

Duke Authors

Cited Authors

  • Jasien, JM; Mikati, MA; Kolarova, M; Smith, B; Thera, S; Lee, P

Published Date

  • April 2021

Published In

Volume / Issue

  • 37 / 4

Start / End Page

  • 1143 - 1150

PubMed ID

  • 33185713

Pubmed Central ID

  • PMC8012220

Electronic International Standard Serial Number (EISSN)

  • 1433-0350

Digital Object Identifier (DOI)

  • 10.1007/s00381-020-04964-1


  • eng

Conference Location

  • Germany