Transplant social worker and donor financial assistance to increase living donor kidney transplants among African Americans: The TALKS Study, a randomized comparative effectiveness trial.

Journal Article (Journal Article)

Lack of donors hinders living donor kidney transplantation (LDKT) for African Americans. We studied the effectiveness of a transplant social worker intervention (TALK SWI) alone or paired with living donor financial assistance to activate African Americans' potential living kidney donors. African Americans (N = 300) on the transplant waiting list were randomly assigned to usual care; TALK SWI; or TALK SWI plus Living Donor Financial Assistance. We quantified differences in live kidney donor activation (composite rate of live donor inquiries, completed new live donor evaluations, or live kidney donation) after 12 months. Participants' mean age was 52 years, 56% were male, and 43% had annual household income less than $40,000. Most previously pursued LDKT. Participants were highly satisfied with TALK social workers, but they rarely utilized Financial Assistance. After 12 months, few (n = 39, 13%) participants had a new donor activation event (35 [12%] new donor inquiries; 17 [6%] new donor evaluations; 4 [1%] LDKT). There were no group differences in donor activation events (subdistribution hazard ratio [95% CI]: 1.09 [0.51-2.30] for TALK SWI and 0.92 [0.42-2.02] for TALK SWI plus Financial Assistance compared to Usual Care, p = 91). Alternative interventions to increase LDKT for African Americans on the waiting list may be needed. Trial registration: (NCT02369354).

Full Text

Duke Authors

Cited Authors

  • Boulware, LE; Sudan, DL; Strigo, TS; Ephraim, PL; Davenport, CA; Pendergast, JF; Pounds, I; Riley, JA; Falkovic, M; Alkon, A; Hill-Briggs, F; Cabacungan, AN; Barrett, TM; Mohottige, D; McElroy, L; Diamantidis, CJ; Ellis, MJ

Published Date

  • June 2021

Published In

Volume / Issue

  • 21 / 6

Start / End Page

  • 2175 - 2187

PubMed ID

  • 33210831

Electronic International Standard Serial Number (EISSN)

  • 1600-6143

Digital Object Identifier (DOI)

  • 10.1111/ajt.16403


  • eng

Conference Location

  • United States