A Potential Role of Interleukin 10 in COVID-19 Pathogenesis.

Journal Article (Journal Article;Review)

A unique feature of the cytokine storm in coronavirus disease 2019 (COVID-19) is the dramatic elevation of interleukin 10 (IL-10). This was thought to be a negative feedback mechanism to suppress inflammation. However, several lines of clinical evidence suggest that dramatic early proinflammatory IL-10 elevation may play a pathological role in COVID-19 severity.

Full Text

Duke Authors

Cited Authors

  • Lu, L; Zhang, H; Dauphars, DJ; He, Y-W

Published Date

  • January 2021

Published In

Volume / Issue

  • 42 / 1

Start / End Page

  • 3 - 5

PubMed ID

  • 33214057

Pubmed Central ID

  • PMC7605819

Electronic International Standard Serial Number (EISSN)

  • 1471-4981

Digital Object Identifier (DOI)

  • 10.1016/j.it.2020.10.012


  • eng

Conference Location

  • England