Skip to main content
Journal cover image

A Potential Role of Interleukin 10 in COVID-19 Pathogenesis.

Publication ,  Journal Article
Lu, L; Zhang, H; Dauphars, DJ; He, Y-W
Published in: Trends Immunol
January 2021

A unique feature of the cytokine storm in coronavirus disease 2019 (COVID-19) is the dramatic elevation of interleukin 10 (IL-10). This was thought to be a negative feedback mechanism to suppress inflammation. However, several lines of clinical evidence suggest that dramatic early proinflammatory IL-10 elevation may play a pathological role in COVID-19 severity.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Trends Immunol

DOI

EISSN

1471-4981

Publication Date

January 2021

Volume

42

Issue

1

Start / End Page

3 / 5

Location

England

Related Subject Headings

  • Severity of Illness Index
  • SARS-CoV-2
  • Models, Immunological
  • Lymphocytes
  • Interleukin-10
  • Interferon-gamma
  • Immunology
  • Humans
  • Epidemics
  • Cytokine Release Syndrome
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Lu, L., Zhang, H., Dauphars, D. J., & He, Y.-W. (2021). A Potential Role of Interleukin 10 in COVID-19 Pathogenesis. Trends Immunol, 42(1), 3–5. https://doi.org/10.1016/j.it.2020.10.012
Lu, Ligong, Hui Zhang, Danielle J. Dauphars, and You-Wen He. “A Potential Role of Interleukin 10 in COVID-19 Pathogenesis.Trends Immunol 42, no. 1 (January 2021): 3–5. https://doi.org/10.1016/j.it.2020.10.012.
Lu L, Zhang H, Dauphars DJ, He Y-W. A Potential Role of Interleukin 10 in COVID-19 Pathogenesis. Trends Immunol. 2021 Jan;42(1):3–5.
Lu, Ligong, et al. “A Potential Role of Interleukin 10 in COVID-19 Pathogenesis.Trends Immunol, vol. 42, no. 1, Jan. 2021, pp. 3–5. Pubmed, doi:10.1016/j.it.2020.10.012.
Lu L, Zhang H, Dauphars DJ, He Y-W. A Potential Role of Interleukin 10 in COVID-19 Pathogenesis. Trends Immunol. 2021 Jan;42(1):3–5.
Journal cover image

Published In

Trends Immunol

DOI

EISSN

1471-4981

Publication Date

January 2021

Volume

42

Issue

1

Start / End Page

3 / 5

Location

England

Related Subject Headings

  • Severity of Illness Index
  • SARS-CoV-2
  • Models, Immunological
  • Lymphocytes
  • Interleukin-10
  • Interferon-gamma
  • Immunology
  • Humans
  • Epidemics
  • Cytokine Release Syndrome