A Potential Role of Interleukin 10 in COVID-19 Pathogenesis.
Publication
, Journal Article
Lu, L; Zhang, H; Dauphars, DJ; He, Y-W
Published in: Trends Immunol
January 2021
A unique feature of the cytokine storm in coronavirus disease 2019 (COVID-19) is the dramatic elevation of interleukin 10 (IL-10). This was thought to be a negative feedback mechanism to suppress inflammation. However, several lines of clinical evidence suggest that dramatic early proinflammatory IL-10 elevation may play a pathological role in COVID-19 severity.
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Published In
Trends Immunol
DOI
EISSN
1471-4981
Publication Date
January 2021
Volume
42
Issue
1
Start / End Page
3 / 5
Location
England
Related Subject Headings
- Severity of Illness Index
- SARS-CoV-2
- Models, Immunological
- Lymphocytes
- Interleukin-10
- Interferon-gamma
- Immunology
- Humans
- Epidemics
- Cytokine Release Syndrome
Citation
APA
Chicago
ICMJE
MLA
NLM
Lu, L., Zhang, H., Dauphars, D. J., & He, Y.-W. (2021). A Potential Role of Interleukin 10 in COVID-19 Pathogenesis. Trends Immunol, 42(1), 3–5. https://doi.org/10.1016/j.it.2020.10.012
Lu, Ligong, Hui Zhang, Danielle J. Dauphars, and You-Wen He. “A Potential Role of Interleukin 10 in COVID-19 Pathogenesis.” Trends Immunol 42, no. 1 (January 2021): 3–5. https://doi.org/10.1016/j.it.2020.10.012.
Lu L, Zhang H, Dauphars DJ, He Y-W. A Potential Role of Interleukin 10 in COVID-19 Pathogenesis. Trends Immunol. 2021 Jan;42(1):3–5.
Lu, Ligong, et al. “A Potential Role of Interleukin 10 in COVID-19 Pathogenesis.” Trends Immunol, vol. 42, no. 1, Jan. 2021, pp. 3–5. Pubmed, doi:10.1016/j.it.2020.10.012.
Lu L, Zhang H, Dauphars DJ, He Y-W. A Potential Role of Interleukin 10 in COVID-19 Pathogenesis. Trends Immunol. 2021 Jan;42(1):3–5.
Published In
Trends Immunol
DOI
EISSN
1471-4981
Publication Date
January 2021
Volume
42
Issue
1
Start / End Page
3 / 5
Location
England
Related Subject Headings
- Severity of Illness Index
- SARS-CoV-2
- Models, Immunological
- Lymphocytes
- Interleukin-10
- Interferon-gamma
- Immunology
- Humans
- Epidemics
- Cytokine Release Syndrome