HIV-1 infection of the kidney: mechanisms and implications.

Journal Article (Journal Article;Review)

People living with HIV are at higher risk for acute and chronic kidney disease compared with uninfected individuals. Kidney disease in this population is multifactorial, with several contributors including HIV infection of kidney cells, chronic inflammation, genetic predisposition, aging, comorbidities, and coinfections. In this review, we provide a summary of recent advancements in the understanding of the mechanisms and implications of HIV infection and kidney disease, with particular focus on the role of direct HIV infection of renal cells.

Full Text

Duke Authors

Cited Authors

  • Hughes, K; Chang, J; Stadtler, H; Wyatt, C; Klotman, M; Blasi, M

Published Date

  • March 1, 2021

Published In

Volume / Issue

  • 35 / 3

Start / End Page

  • 359 - 367

PubMed ID

  • 33229896

Pubmed Central ID

  • PMC7855797

Electronic International Standard Serial Number (EISSN)

  • 1473-5571

Digital Object Identifier (DOI)

  • 10.1097/QAD.0000000000002753


  • eng

Conference Location

  • England