kdr-Type resistance in insects with special reference to the German cockroach, Blattella germanica.

Journal Article (Review;Journal Article)

The phenomenon of knockdown resistance (kdr) was first noted in the housefly (Musca domestica), and has subsequently be found (i.e. kdr-type resistance) in several other insect pests including the German cockroach (Blattella germanica). This type of resistance causes insensitivity of the nervous system to pyrethroids, DDT and a limited number of sodium channel neurotoxins. In the German cockroach, kdr-type resistance is incompletely recessive, monogenic and not sex linked or due to cytoplasmic factors. Additionally, kdr-type resistance is not associated with a change in sodium channel density. kdr or kdr-type loci are tightly linked or identical to the para-homologous sodium channel locus in German cockroach, housefly and tobacco budworm (Heliothis virescens), suggesting that kdr and kdr-type resistance are due to mutations in the para-homologous sodium channel gene. kdr-Type resistance in the German cockroach appears similar, although not necessarily identical, to kdr in houseflies.

Full Text

Duke Authors

Cited Authors

  • Scott, JG; Dong, K

Published Date

  • October 1994

Published In

Volume / Issue

  • 109 / 2-3

Start / End Page

  • 191 - 198

PubMed ID

  • 7553340

Electronic International Standard Serial Number (EISSN)

  • 1879-1107

International Standard Serial Number (ISSN)

  • 1096-4959

Digital Object Identifier (DOI)

  • 10.1016/0305-0491(94)90002-7

Language

  • eng