The next generation of antiemetics for the management of postoperative nausea and vomiting.
Publication
, Journal Article
Tan, HS; Dewinter, G; Habib, AS
Published in: Best Pract Res Clin Anaesthesiol
December 2020
Postoperative nausea and vomiting (PONV) afflict approximately 30% of patients overall and up to 80% of high-risk patients after surgery. Optimal pharmacological prophylaxis of PONV is challenging as it necessitates the consideration of PONV risk, drug efficacy, and potential adverse effects. Despite significant advances in our understanding of the pathophysiology and risk factors of PONV, its incidence has remained largely unchanged. Newer antiemetics have been introduced that may have improved safety profiles, longer duration of action, and better efficacy. This review aims to summarize the recent developments pertaining to these new agents and their potential application toward the management of PONV.
Duke Scholars
Published In
Best Pract Res Clin Anaesthesiol
DOI
EISSN
1878-1608
Publication Date
December 2020
Volume
34
Issue
4
Start / End Page
759 / 769
Location
Netherlands
Related Subject Headings
- Serotonin 5-HT3 Receptor Antagonists
- Randomized Controlled Trials as Topic
- Postoperative Nausea and Vomiting
- Palonosetron
- Neurokinin-1 Receptor Antagonists
- Humans
- Drug Therapy, Combination
- Dopamine Antagonists
- Disease Management
- Aprepitant
Citation
APA
Chicago
ICMJE
MLA
NLM
Tan, H. S., Dewinter, G., & Habib, A. S. (2020). The next generation of antiemetics for the management of postoperative nausea and vomiting. Best Pract Res Clin Anaesthesiol, 34(4), 759–769. https://doi.org/10.1016/j.bpa.2020.11.004
Tan, Hon Sen, Geertrui Dewinter, and Ashraf S. Habib. “The next generation of antiemetics for the management of postoperative nausea and vomiting.” Best Pract Res Clin Anaesthesiol 34, no. 4 (December 2020): 759–69. https://doi.org/10.1016/j.bpa.2020.11.004.
Tan HS, Dewinter G, Habib AS. The next generation of antiemetics for the management of postoperative nausea and vomiting. Best Pract Res Clin Anaesthesiol. 2020 Dec;34(4):759–69.
Tan, Hon Sen, et al. “The next generation of antiemetics for the management of postoperative nausea and vomiting.” Best Pract Res Clin Anaesthesiol, vol. 34, no. 4, Dec. 2020, pp. 759–69. Pubmed, doi:10.1016/j.bpa.2020.11.004.
Tan HS, Dewinter G, Habib AS. The next generation of antiemetics for the management of postoperative nausea and vomiting. Best Pract Res Clin Anaesthesiol. 2020 Dec;34(4):759–769.
Published In
Best Pract Res Clin Anaesthesiol
DOI
EISSN
1878-1608
Publication Date
December 2020
Volume
34
Issue
4
Start / End Page
759 / 769
Location
Netherlands
Related Subject Headings
- Serotonin 5-HT3 Receptor Antagonists
- Randomized Controlled Trials as Topic
- Postoperative Nausea and Vomiting
- Palonosetron
- Neurokinin-1 Receptor Antagonists
- Humans
- Drug Therapy, Combination
- Dopamine Antagonists
- Disease Management
- Aprepitant