Compressive anisotropy of sheet and strut based porous Ti-6Al-4V scaffolds.

Journal Article (Journal Article)

Porous metallic scaffolds show promise in orthopedic applications due to favorable mechanical and biological properties. In vivo stress conditions on orthopedic implants are complex, often including multiaxial loading across off axis orientations. In this study, unit cell orientation was rotated in the XZ plane of a strut-based architecture, Diamond Crystal, and two sheet-based, triply periodic minimal surface (TPMS) architectures, Schwartz D and Gyroid. Sheet-based architectures exhibited higher peak compressive strength, yield strength and strain at peak stress than the strut-based architecture. All three topologies demonstrated an orientational dependence in mechanical properties. There was a greater degree of anisotropy (49%) in strut-based architecture than in either TPMS architectures (18-21%). These results support the superior strength and advantageous isotropic mechanical properties of sheet-based TPMS architectures relative to strut-based architectures, as well as highlighting the importance of considering anisotropic properties of lattice scaffolds for use in tissue engineering.

Full Text

Duke Authors

Cited Authors

  • Barber, H; Kelly, CN; Nelson, K; Gall, K

Published Date

  • March 2021

Published In

Volume / Issue

  • 115 /

Start / End Page

  • 104243 -

PubMed ID

  • 33307487

Electronic International Standard Serial Number (EISSN)

  • 1878-0180

International Standard Serial Number (ISSN)

  • 1751-6161

Digital Object Identifier (DOI)

  • 10.1016/j.jmbbm.2020.104243


  • eng