Intravascular optical coherence tomography light scattering artifacts: merry-go-rounding, blooming, and ghost struts.

Journal Article (Journal Article)

We sought to elucidate the mechanisms underlying two common intravascular optical coherence tomography (IV-OCT) artifacts that occur when imaging metallic stents: “merry-go-rounding” (MGR), which is an increase in strut arc length (SAL), and “blooming,” which is an increase in the strut reflection thickness (blooming thickness). Due to uncontrollable variables that occur in vivo, we performed an in vitro assessment of MGR and blooming in stented vessel phantoms. Using Xience V and Driver stents, we examined the effects of catheter offset, intimal strut coverage, and residual blood on SAL and blooming thickness in IV-OCT images. Catheter offset and strut coverage both caused minor MGR, while the greatest MGR effect resulted from light scattering by residual blood in the vessel lumen, with 1% hematocrit (Hct) causing a more than fourfold increase in SAL compared with saline (p<0.001 ). Residual blood also resulted in blooming, with blooming thickness more than doubling when imaged in 0.5% Hct compared with saline (p<0.001 ). We demonstrate that a previously undescribed mechanism, light scattering by residual blood in the imaging field, is the predominant cause of MGR. Light scattering also results in blooming, and a newly described artifact, three-dimensional-MGR, which results in “ghost struts” in B-scans.

Full Text

Duke Authors

Cited Authors

  • Mancuso, JJ; Halaney, DL; Elahi, S; Ho, D; Wang, T; Ouyang, Y; Dijkstra, J; Milner, TE; Feldman, MD

Published Date

  • December 2014

Published In

Volume / Issue

  • 19 / 12

Start / End Page

  • 126017 -

PubMed ID

  • 25545341

Pubmed Central ID

  • 25545341

Electronic International Standard Serial Number (EISSN)

  • 1560-2281

International Standard Serial Number (ISSN)

  • 1083-3668

Digital Object Identifier (DOI)

  • 10.1117/1.jbo.19.12.126017

Language

  • eng