Feasibility of Mild Traumatic Brain Injury Assessment Based on Cardiovascular Response to Postural Change.
Journal Article (Journal Article)
Objective
To determine the feasibility of short-term cardiovascular responses to postural change as a screening tool for mild traumatic brain injury (mTBI), using heart rate metrics that can be measured with a wearable electrocardiogram sensor.Setting
Military TBI clinic.Design
Data collected from active-duty service members who had sustained a medically diagnosed mTBI within the prior 72 hours and from age- and sex-matched controls. Cardiac data collected while participants performed a sequence of postural changes.Main measures
Model classification compared with clinical mTBI diagnosis.Results
Cardiac biomarkers of mTBI were identified and logistic regression classifiers for mTBI were developed from different subsets of biomarkers. The best model achieved 90% sensitivity and 69% specificity using data from 2 different postural changes.Conclusion
Noninvasive measurement of cardiovascular response to postural change is a promising approach for field-deployable post-mTBI screening.Full Text
Duke Authors
Cited Authors
- Russell, KN; Preble, EA; Hegarty-Craver, M; Arrieux, JP; Cole, WR; Choi, YS; Grego, S; Rae Olmsted, K; Gilchrist, KH
Published Date
- September 2020
Published In
Volume / Issue
- 35 / 5
Start / End Page
- E422 - E428
PubMed ID
- 32472839
Electronic International Standard Serial Number (EISSN)
- 1550-509X
International Standard Serial Number (ISSN)
- 0885-9701
Digital Object Identifier (DOI)
- 10.1097/htr.0000000000000582
Language
- eng