Heart Sound Analysis in Individuals Supported with Left Ventricular Assist Device: A First Look

Conference Paper

The left ventricular assist device (LVAD) has emerged as a bridge or alternative to heart transplant in individuals with advanced heart failure. However, the LVAD recipient population currently faces high rehospitalization rates. Remote analysis of precordial sounds in LVAD recipients may improve aftercare through early detection of complications. Prior work on analyses of precordial sounds in LVAD recipients focused on identifying pump thrombosis. Here, we focus on analyzing intrinsic precordial sounds to provide insight into intrinsic cardiac function. We analyzed a dataset of patient-acquired recordings of precordial sounds in LVAD recipients. We developed a signal processing pipeline to separate LVAD-generated sounds from other precordial sounds, making heart sound analysis in LVAD recipients feasible. Unsupervised clustering of features extracted from LVAD-mitigated sounds revealed subgroups of subjects possessing heart sounds with distinct frequency characteristics. The results provide preliminary evidence for the potential utility of exploring heart sound analysis in LVAD recipients for remote monitoring.

Full Text

Duke Authors

Cited Authors

  • Chen, XJ; Collins, LM; Patel, PA; Karra, R; Mainsah, BO

Published Date

  • September 13, 2020

Published In

Volume / Issue

  • 2020-September /

Electronic International Standard Serial Number (EISSN)

  • 2325-887X

International Standard Serial Number (ISSN)

  • 2325-8861

International Standard Book Number 13 (ISBN-13)

  • 9781728173825

Digital Object Identifier (DOI)

  • 10.22489/CinC.2020.080

Citation Source

  • Scopus