The State of Melanoma: Emergent Challenges and Opportunities.

Journal Article (Journal Article)

Five years ago, the Melanoma Research Foundation (MRF) conducted an assessment of the challenges and opportunities facing the melanoma research community and patients with melanoma. Since then, remarkable progress has been made on both the basic and clinical research fronts. However, the incidence, recurrence, and death rates for melanoma remain unacceptably high and significant challenges remain. Hence, the MRF Scientific Advisory Council and Breakthrough Consortium, a group that includes clinicians and scientists, reconvened to facilitate intensive discussions on thematic areas essential to melanoma researchers and patients alike, prevention, detection, diagnosis, metastatic dormancy and progression, response and resistance to targeted and immune-based therapy, and the clinical consequences of COVID-19 for patients with melanoma and providers. These extensive discussions helped to crystalize our understanding of the challenges and opportunities facing the broader melanoma community today. In this report, we discuss the progress made since the last MRF assessment, comment on what remains to be overcome, and offer recommendations for the best path forward.

Full Text

Duke Authors

Cited Authors

  • Atkins, MB; Curiel-Lewandrowski, C; Fisher, DE; Swetter, SM; Tsao, H; Aguirre-Ghiso, JA; Soengas, MS; Weeraratna, AT; Flaherty, KT; Herlyn, M; Sosman, JA; Tawbi, HA; Pavlick, AC; Cassidy, PB; Chandra, S; Chapman, PB; Daud, A; Eroglu, Z; Ferris, LK; Fox, BA; Gershenwald, JE; Gibney, GT; Grossman, D; Hanks, BA; Hanniford, D; Hernando, E; Jeter, JM; Johnson, DB; Khleif, SN; Kirkwood, JM; Leachman, SA; Mays, D; Nelson, KC; Sondak, VK; Sullivan, RJ; Merlino, G; Melanoma Research Foundation,

Published Date

  • May 15, 2021

Published In

Volume / Issue

  • 27 / 10

Start / End Page

  • 2678 - 2697

PubMed ID

  • 33414132

Pubmed Central ID

  • PMC8127340

Electronic International Standard Serial Number (EISSN)

  • 1557-3265

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-20-4092


  • eng

Conference Location

  • United States