A role for the root cap in root branching revealed by the non-auxin probe naxillin.

Journal Article (Journal Article)

The acquisition of water and nutrients by plant roots is a fundamental aspect of agriculture and strongly depends on root architecture. Root branching and expansion of the root system is achieved through the development of lateral roots and is to a large extent controlled by the plant hormone auxin. However, the pleiotropic effects of auxin or auxin-like molecules on root systems complicate the study of lateral root development. Here we describe a small-molecule screen in Arabidopsis thaliana that identified naxillin as what is to our knowledge the first non-auxin-like molecule that promotes root branching. By using naxillin as a chemical tool, we identified a new function for root cap-specific conversion of the auxin precursor indole-3-butyric acid into the active auxin indole-3-acetic acid and uncovered the involvement of the root cap in root branching. Delivery of an auxin precursor in peripheral tissues such as the root cap might represent an important mechanism shaping root architecture.

Full Text

Duke Authors

Cited Authors

  • De Rybel, B; Audenaert, D; Xuan, W; Overvoorde, P; Strader, LC; Kepinski, S; Hoye, R; Brisbois, R; Parizot, B; Vanneste, S; Liu, X; Gilday, A; Graham, IA; Nguyen, L; Jansen, L; Njo, MF; Inzé, D; Bartel, B; Beeckman, T

Published Date

  • September 2012

Published In

Volume / Issue

  • 8 / 9

Start / End Page

  • 798 - 805

PubMed ID

  • 22885787

Pubmed Central ID

  • PMC3735367

Electronic International Standard Serial Number (EISSN)

  • 1552-4469

International Standard Serial Number (ISSN)

  • 1552-4450

Digital Object Identifier (DOI)

  • 10.1038/nchembio.1044


  • eng