Skip to main content
Journal cover image
Cassidy and Allanson's Management of Genetic Syndromes, Fourth Edition

Down syndrome

Publication ,  Chapter
Korlimarla, A; Hart, S; Spiridigliozzi, G; Kishnani, P
February 19, 2021

Down syndrome is the most common identifiable genetic cause of intellectual disability. The facial appearance of individuals with Down syndrome is highly characteristic and is frequently associated with other minor anomalies and malformations of other body systems, most importantly the cardiovascular and gastrointestinal systems. Individuals with Down syndrome also have an increased likelihood of a number of medical complications including those of the thyroid gland, and the gastrointestinal, upper‐respiratory, audiologic, hematological, and neurological systems. It is thus important for persons with Down syndrome to be followed in a systematic fashion and have access to appropriate specialists to anticipate, prevent, or modify potential complications. Current research continues to shed light on many behavioral and medical aspects of Down syndrome, but questions remain about the relationship between the trisomy of chromosome 21, the developmental and behavioral pattern, and the health complications.

Duke Scholars

DOI

ISBN

9781119432692

Publication Date

February 19, 2021

Start / End Page

355 / 387

Publisher

© 2021 John Wiley & Sons, Inc.
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Korlimarla, A., Hart, S., Spiridigliozzi, G., & Kishnani, P. (2021). Down syndrome. In . John C. Carey  Agatino Battaglia  David Viskochil  Suzanne B. Cassidy (Ed.), Cassidy and Allanson’s Management of Genetic Syndromes, Fourth Edition (pp. 355–387). © 2021 John Wiley & Sons, Inc. https://doi.org/10.1002/9781119432692.ch24
Korlimarla, Aditi, Sarah Hart, Gail Spiridigliozzi, and Priya Kishnani. “Down syndrome.” In Cassidy and Allanson’s Management of Genetic Syndromes, Fourth Edition, edited by Priya John C. Carey  Agatino Battaglia  David Viskochil  Suzanne B. Cassidy, 355–87. © 2021 John Wiley & Sons, Inc., 2021. https://doi.org/10.1002/9781119432692.ch24.
Korlimarla A, Hart S, Spiridigliozzi G, Kishnani P. Down syndrome. In: John C. Carey  Agatino Battaglia  David Viskochil  Suzanne B. Cassidy, editor. Cassidy and Allanson’s Management of Genetic Syndromes, Fourth Edition. © 2021 John Wiley & Sons, Inc.; 2021. p. 355–87.
Korlimarla, Aditi, et al. “Down syndrome.” Cassidy and Allanson’s Management of Genetic Syndromes, Fourth Edition, edited by Priya John C. Carey  Agatino Battaglia  David Viskochil  Suzanne B. Cassidy, © 2021 John Wiley & Sons, Inc., 2021, pp. 355–87. Manual, doi:10.1002/9781119432692.ch24.
Korlimarla A, Hart S, Spiridigliozzi G, Kishnani P. Down syndrome. In: John C. Carey  Agatino Battaglia  David Viskochil  Suzanne B. Cassidy, editor. Cassidy and Allanson’s Management of Genetic Syndromes, Fourth Edition. © 2021 John Wiley & Sons, Inc.; 2021. p. 355–387.
Journal cover image

DOI

ISBN

9781119432692

Publication Date

February 19, 2021

Start / End Page

355 / 387

Publisher

© 2021 John Wiley & Sons, Inc.