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Diagnostic, Predictive and Prognostic Molecular Biomarkers in Pancreatic Cancer: An Overview for Clinicians.

Publication ,  Journal Article
Giannis, D; Moris, D; Barbas, AS
Published in: Cancers (Basel)
March 3, 2021

Pancreatic ductal adenocarcinoma (PDAC) is the most common pancreatic malignancy and is associated with aggressive tumor behavior and poor prognosis. Most patients with PDAC present with an advanced disease stage and treatment-resistant tumors. The lack of noninvasive tests for PDAC diagnosis and survival prediction mandates the identification of novel biomarkers. The early identification of high-risk patients and patients with PDAC is of utmost importance. In addition, the identification of molecules that are associated with tumor biology, aggressiveness, and metastatic potential is crucial to predict survival and to provide patients with personalized treatment regimens. In this review, we summarize the current literature and focus on newer biomarkers, which are continuously added to the armamentarium of PDAC screening, predictive tools, and prognostic tools.

Duke Scholars

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Published In

Cancers (Basel)

DOI

ISSN

2072-6694

Publication Date

March 3, 2021

Volume

13

Issue

5

Location

Switzerland

Related Subject Headings

  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis
 

Citation

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ICMJE
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Giannis, D., Moris, D., & Barbas, A. S. (2021). Diagnostic, Predictive and Prognostic Molecular Biomarkers in Pancreatic Cancer: An Overview for Clinicians. Cancers (Basel), 13(5). https://doi.org/10.3390/cancers13051071
Giannis, Dimitrios, Dimitrios Moris, and Andrew S. Barbas. “Diagnostic, Predictive and Prognostic Molecular Biomarkers in Pancreatic Cancer: An Overview for Clinicians.Cancers (Basel) 13, no. 5 (March 3, 2021). https://doi.org/10.3390/cancers13051071.
Giannis, Dimitrios, et al. “Diagnostic, Predictive and Prognostic Molecular Biomarkers in Pancreatic Cancer: An Overview for Clinicians.Cancers (Basel), vol. 13, no. 5, Mar. 2021. Pubmed, doi:10.3390/cancers13051071.

Published In

Cancers (Basel)

DOI

ISSN

2072-6694

Publication Date

March 3, 2021

Volume

13

Issue

5

Location

Switzerland

Related Subject Headings

  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis