Biological Phase Separation and Biomolecular Condensates in Plants.

Journal Article (Journal Article)

A surge in research focused on understanding the physical principles governing the formation, properties, and function of membraneless compartments has occurred over the past decade. Compartments such as the nucleolus, stress granules, and nuclear speckles have been designated as biomolecular condensates to describe their shared property of spatially concentrating biomolecules. Although this research has historically been carried out in animal and fungal systems, recent work has begun to explore whether these same principles are relevant in plants. Effectively understanding and studying biomolecular condensates require interdisciplinary expertise that spans cell biology, biochemistry, and condensed matter physics and biophysics. As such, some involved concepts may be unfamiliar to any given individual. This review focuses on introducing concepts essential to the study of biomolecular condensates and phase separation for biologists seeking to carry out research in this area and further examines aspects of biomolecular condensates that are relevant to plant systems. Expected final online publication date for the Annual Review of Plant Biology , Volume 72 is May 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

Full Text

Duke Authors

Cited Authors

  • Emenecker, RJ; Holehouse, AS; Strader, LC

Published Date

  • March 8, 2021

Published In

PubMed ID

  • 33684296

Electronic International Standard Serial Number (EISSN)

  • 1545-2123

International Standard Serial Number (ISSN)

  • 1543-5008

Digital Object Identifier (DOI)

  • 10.1146/annurev-arplant-081720-015238

Language

  • eng