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Research Techniques Made Simple: Developing and Validating QOL Outcome Measures for Skin Diseases.

Publication ,  Journal Article
Braun, H; Yeung, H; Chen, SC
Published in: J Invest Dermatol
October 2020

Skin conditions can significantly impact QOL. Dermatology QOL instruments may measure general skin-specific, disease-specific, or condition-specific QOL. Key components in the development of QOL instruments include (i) instrument and conceptual framework development, (ii) items and conceptual framework refinement, (iii) psychometric property testing, and (iv) clinical meaning and interpretation. First, a theoretical framework based on existing literature and subject experts (i.e., patients living with these conditions) is developed. By administering the pilot instrument to patients, the theoretical framework undergoes testing and revision to improve the instrument. At initial testing, construct validity and internal consistency can be assessed. At 72-hour follow-up, test-retest reliability can be determined. Responsiveness is determined by a follow-up test at a time point reasonable to allow for a detectable change in condition. The clinical meaning of the results must then be determined to allow clinical and statistical interpretation.

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Published In

J Invest Dermatol

DOI

EISSN

1523-1747

Publication Date

October 2020

Volume

140

Issue

10

Start / End Page

1888 / 1892.e1

Location

United States

Related Subject Headings

  • Skin Diseases
  • Research Design
  • Reproducibility of Results
  • Quality of Life
  • Psychometrics
  • Outcome Assessment, Health Care
  • Humans
  • Dermatology & Venereal Diseases
  • 3202 Clinical sciences
  • 1112 Oncology and Carcinogenesis
 

Citation

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Braun, H., Yeung, H., & Chen, S. C. (2020). Research Techniques Made Simple: Developing and Validating QOL Outcome Measures for Skin Diseases. J Invest Dermatol, 140(10), 1888-1892.e1. https://doi.org/10.1016/j.jid.2020.04.024
Braun, Hayley, Howa Yeung, and Suephy C. Chen. “Research Techniques Made Simple: Developing and Validating QOL Outcome Measures for Skin Diseases.J Invest Dermatol 140, no. 10 (October 2020): 1888-1892.e1. https://doi.org/10.1016/j.jid.2020.04.024.
Braun H, Yeung H, Chen SC. Research Techniques Made Simple: Developing and Validating QOL Outcome Measures for Skin Diseases. J Invest Dermatol. 2020 Oct;140(10):1888-1892.e1.
Braun, Hayley, et al. “Research Techniques Made Simple: Developing and Validating QOL Outcome Measures for Skin Diseases.J Invest Dermatol, vol. 140, no. 10, Oct. 2020, pp. 1888-1892.e1. Pubmed, doi:10.1016/j.jid.2020.04.024.
Braun H, Yeung H, Chen SC. Research Techniques Made Simple: Developing and Validating QOL Outcome Measures for Skin Diseases. J Invest Dermatol. 2020 Oct;140(10):1888-1892.e1.
Journal cover image

Published In

J Invest Dermatol

DOI

EISSN

1523-1747

Publication Date

October 2020

Volume

140

Issue

10

Start / End Page

1888 / 1892.e1

Location

United States

Related Subject Headings

  • Skin Diseases
  • Research Design
  • Reproducibility of Results
  • Quality of Life
  • Psychometrics
  • Outcome Assessment, Health Care
  • Humans
  • Dermatology & Venereal Diseases
  • 3202 Clinical sciences
  • 1112 Oncology and Carcinogenesis