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Pruritus assessment tools for 6 to 7-year-old children: KidsItchyQoL and ItchyQuant.

Publication ,  Journal Article
Kong, HE; Francois, S; Smith, S; Spraker, M; Lawley, LP; Lee, G; Chen, K-H; Roberts, JS; Chen, SC
Published in: Pediatr Dermatol
May 2021

BACKGROUND/OBJECTIVES: Measures of pruritus severity and quality of life (QoL) are necessary for the development of therapeutics for children with chronic pruritus. In children, questionnaires need to be developed for specific age groups given the differences in cognitive levels. In this study, we aimed to develop tools to assess QoL and pruritus severity in children 6 to 7-years-old with chronic pruritus. METHODS: Based on open interviews with children, we developed a cartoon-annotated QoL instrument, KidsItchyQoL, and validated an existing pruritus severity instrument, ItchyQuant, that measures pruritus impact and severity for the preceding week. Both instruments were administered to 100 children aged 6-7 years with chronic pruritus. The data were analyzed for reliability, reproducibility, construct validity, and responsiveness. RESULTS: We found the 14-item KidsItchyQoL to be reliable (Cronbach's α = 0.846) and reproducible (intraclass correlation coefficient (ICC) = 0.66) as was the ItchyQuant (ICC = 0.47). With respect to construct validity, examination of eigenvalues of the inter-item polychoric correlation matrix suggested three dominant factors. A subsequent confirmatory factor analysis suggested that a 3-dimensional simple structure model with correlated factors provided a reasonable data representation. The responsiveness of KidsItchyQoL and ItchyQuant (P = .005, GLM procedure) were demonstrated with scores changing as expected with the self-reported change of itch severity. CONCLUSIONS: These results demonstrate promise for a new set of reliable research tools to assess QoL and pruritus severity in children 6 to 7 years of age.

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Published In

Pediatr Dermatol

DOI

EISSN

1525-1470

Publication Date

May 2021

Volume

38

Issue

3

Start / End Page

591 / 601

Location

United States

Related Subject Headings

  • Surveys and Questionnaires
  • Severity of Illness Index
  • Reproducibility of Results
  • Quality of Life
  • Pruritus
  • Humans
  • Dermatology & Venereal Diseases
  • Child
  • 3213 Paediatrics
  • 3202 Clinical sciences
 

Citation

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Kong, H. E., Francois, S., Smith, S., Spraker, M., Lawley, L. P., Lee, G., … Chen, S. C. (2021). Pruritus assessment tools for 6 to 7-year-old children: KidsItchyQoL and ItchyQuant. Pediatr Dermatol, 38(3), 591–601. https://doi.org/10.1111/pde.14563
Kong, Ha Eun, Sandy Francois, Shelby Smith, Mary Spraker, Leslie P. Lawley, Grace Lee, Kuang-Ho Chen, James S. Roberts, and Suephy C. Chen. “Pruritus assessment tools for 6 to 7-year-old children: KidsItchyQoL and ItchyQuant.Pediatr Dermatol 38, no. 3 (May 2021): 591–601. https://doi.org/10.1111/pde.14563.
Kong HE, Francois S, Smith S, Spraker M, Lawley LP, Lee G, et al. Pruritus assessment tools for 6 to 7-year-old children: KidsItchyQoL and ItchyQuant. Pediatr Dermatol. 2021 May;38(3):591–601.
Kong, Ha Eun, et al. “Pruritus assessment tools for 6 to 7-year-old children: KidsItchyQoL and ItchyQuant.Pediatr Dermatol, vol. 38, no. 3, May 2021, pp. 591–601. Pubmed, doi:10.1111/pde.14563.
Kong HE, Francois S, Smith S, Spraker M, Lawley LP, Lee G, Chen K-H, Roberts JS, Chen SC. Pruritus assessment tools for 6 to 7-year-old children: KidsItchyQoL and ItchyQuant. Pediatr Dermatol. 2021 May;38(3):591–601.
Journal cover image

Published In

Pediatr Dermatol

DOI

EISSN

1525-1470

Publication Date

May 2021

Volume

38

Issue

3

Start / End Page

591 / 601

Location

United States

Related Subject Headings

  • Surveys and Questionnaires
  • Severity of Illness Index
  • Reproducibility of Results
  • Quality of Life
  • Pruritus
  • Humans
  • Dermatology & Venereal Diseases
  • Child
  • 3213 Paediatrics
  • 3202 Clinical sciences