Amniotic fluid embolus: Can we affect the outcome?

Journal Article (Review;Journal)

Purpose of review: Amniotic fluid embolism is a rare catastrophe unique to pregnancy. Its mortality rate remains high despite efforts at prompt and aggressive management protocols, highlighting the need to maintain a high index of suspicion. Recent findings: The intrusion of amniotic fluid into the maternal bloodstream may lead in certain women to a complex series of physiological reactions mimicking those seen in human anaphylaxis or sepsis, negating the purely embolic phenomenon theory as previously understood. The clinical picture is the sudden onset of cardiovascular collapse, cyanosis, haemorrhage or disseminated intravascular coagulopathy, during or soon after delivery. Summary: The mainstay of a successful outcome remains the identification of high-risk patients, as well as early clinical diagnosis and management.

Full Text

Duke Authors

Cited Authors

  • Ayoub, CM; Zreik, TG; Dabbous, AS; Baraka, AS

Published Date

  • June 1, 2003

Published In

Volume / Issue

  • 16 / 3

Start / End Page

  • 257 - 261

International Standard Serial Number (ISSN)

  • 0952-7907

Digital Object Identifier (DOI)

  • 10.1097/00001503-200306000-00003

Citation Source

  • Scopus