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Changes in resistances of endotracheal tubes with reductions in the cross-sectional area.

Publication ,  Journal Article
El-Khatib, MF; Husari, A; Jamaleddine, GW; Ayoub, CM; Bou-Khalil, P
Published in: Eur J Anaesthesiol
April 2008

BACKGROUND AND OBJECTIVES: Partial obstruction of endotracheal tubes due to accumulation of secretions and mucus plugs can increase the tube resistance and subsequently impose increased resistive load on the patient. This study was performed to determine the changes in the resistance of endotracheal tubes of sizes 7.5, 8.0 and 8.5 mm with different degrees and locations of endotracheal tube narrowing. METHODS: Reductions of 10%, 25%, 50% and 75% in the endotracheal tube's cross-sectional areas were created at different sites along the axes of the tube connected to an artificial lung. While ventilating with a constant inspiratory flow, a 1 s end-inspiratory occlusion manoeuvre was applied and the resulting plateau pressure was determined. The resistance was calculated as (peak airway pressure--plateau pressure)/peak inspiratory flow. RESULTS: Significant increases in the endotracheal tube's resistances were observed as the tube's cross-sectional area reduction was increased from 25% to 50% and from 50% to 75% for the 7.5 mm endotracheal tube, from 25% to 50% for the 8.0 mm endotracheal tube, and from 50% to 75% for the 8.5 mm endotracheal tube. Changes of the endotracheal tube resistances were not affected by the site of cross-sectional area reductions along the axes of the tubes. CONCLUSIONS: For endotracheal tubes of sizes 7.5, 8.0 and 8.5 mm, significant changes in the tubes resistances are observed when the partial obstructions of the tubes exceed certain critical values. The location of the partial obstruction did not affect the changes in the endotracheal tube resistances.

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Published In

Eur J Anaesthesiol

DOI

EISSN

1365-2346

Publication Date

April 2008

Volume

25

Issue

4

Start / End Page

275 / 279

Location

England

Related Subject Headings

  • Work of Breathing
  • Respiration, Artificial
  • Mucus
  • Intubation, Intratracheal
  • Humans
  • Equipment Design
  • Anesthesiology
  • Airway Resistance
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

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El-Khatib, M. F., Husari, A., Jamaleddine, G. W., Ayoub, C. M., & Bou-Khalil, P. (2008). Changes in resistances of endotracheal tubes with reductions in the cross-sectional area. Eur J Anaesthesiol, 25(4), 275–279. https://doi.org/10.1017/S0265021507003134
El-Khatib, M. F., A. Husari, G. W. Jamaleddine, C. M. Ayoub, and P. Bou-Khalil. “Changes in resistances of endotracheal tubes with reductions in the cross-sectional area.Eur J Anaesthesiol 25, no. 4 (April 2008): 275–79. https://doi.org/10.1017/S0265021507003134.
El-Khatib MF, Husari A, Jamaleddine GW, Ayoub CM, Bou-Khalil P. Changes in resistances of endotracheal tubes with reductions in the cross-sectional area. Eur J Anaesthesiol. 2008 Apr;25(4):275–9.
El-Khatib, M. F., et al. “Changes in resistances of endotracheal tubes with reductions in the cross-sectional area.Eur J Anaesthesiol, vol. 25, no. 4, Apr. 2008, pp. 275–79. Pubmed, doi:10.1017/S0265021507003134.
El-Khatib MF, Husari A, Jamaleddine GW, Ayoub CM, Bou-Khalil P. Changes in resistances of endotracheal tubes with reductions in the cross-sectional area. Eur J Anaesthesiol. 2008 Apr;25(4):275–279.
Journal cover image

Published In

Eur J Anaesthesiol

DOI

EISSN

1365-2346

Publication Date

April 2008

Volume

25

Issue

4

Start / End Page

275 / 279

Location

England

Related Subject Headings

  • Work of Breathing
  • Respiration, Artificial
  • Mucus
  • Intubation, Intratracheal
  • Humans
  • Equipment Design
  • Anesthesiology
  • Airway Resistance
  • 3202 Clinical sciences
  • 1103 Clinical Sciences