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Reliability of quantification measures of actinic keratosis.

Publication ,  Journal Article
Chen, SC; Hill, ND; Veledar, E; Swetter, SM; Weinstock, MA
Published in: Br J Dermatol
December 2013

BACKGROUND: Enumerating actinic keratoses (AKs) is highly variable but important to standardize as new therapies are emerging. OBJECTIVES: To assess the reliability of four different methods used to quantify AKs and to investigate whether a consensus meeting affects the reliability. METHODS: This was a single-blinded study of 12 experienced dermatologist raters counting AKs on the face and ears of nine subjects before and after a consensus meeting. Raters were recruited from investigators of a multicentre Veterans Affairs cooperative study. The intraclass correlation coefficient (ICC) among raters for pre- and post-consensus evaluations was the primary outcome measure. RESULTS: Of the four assessment methods, the 'total count' method had the greatest ICC for both pre- (0·18, P = 0·04) and post-consensus (0·66, P = < 0·0001) assessments. Total count was also the only pre-consensus ICC for which the null hypothesis of no association among assessments was rejected. CONCLUSIONS: Total AK count appears to be the most reliable measure of quantifying AKs on the face and ears. Educational consensus discussion prior to assessment improves reliability of this measure.

Duke Scholars

Published In

Br J Dermatol

DOI

EISSN

1365-2133

Publication Date

December 2013

Volume

169

Issue

6

Start / End Page

1219 / 1222

Location

England

Related Subject Headings

  • Single-Blind Method
  • Reproducibility of Results
  • Observer Variation
  • Middle Aged
  • Male
  • Keratosis, Actinic
  • Humans
  • Female
  • Dermatology & Venereal Diseases
  • Dermatology
 

Citation

APA
Chicago
ICMJE
MLA
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Chen, S. C., Hill, N. D., Veledar, E., Swetter, S. M., & Weinstock, M. A. (2013). Reliability of quantification measures of actinic keratosis. Br J Dermatol, 169(6), 1219–1222. https://doi.org/10.1111/bjd.12591
Chen, S. C., N. D. Hill, E. Veledar, S. M. Swetter, and M. A. Weinstock. “Reliability of quantification measures of actinic keratosis.Br J Dermatol 169, no. 6 (December 2013): 1219–22. https://doi.org/10.1111/bjd.12591.
Chen SC, Hill ND, Veledar E, Swetter SM, Weinstock MA. Reliability of quantification measures of actinic keratosis. Br J Dermatol. 2013 Dec;169(6):1219–22.
Chen, S. C., et al. “Reliability of quantification measures of actinic keratosis.Br J Dermatol, vol. 169, no. 6, Dec. 2013, pp. 1219–22. Pubmed, doi:10.1111/bjd.12591.
Chen SC, Hill ND, Veledar E, Swetter SM, Weinstock MA. Reliability of quantification measures of actinic keratosis. Br J Dermatol. 2013 Dec;169(6):1219–1222.
Journal cover image

Published In

Br J Dermatol

DOI

EISSN

1365-2133

Publication Date

December 2013

Volume

169

Issue

6

Start / End Page

1219 / 1222

Location

England

Related Subject Headings

  • Single-Blind Method
  • Reproducibility of Results
  • Observer Variation
  • Middle Aged
  • Male
  • Keratosis, Actinic
  • Humans
  • Female
  • Dermatology & Venereal Diseases
  • Dermatology