A daily skincare regimen with a unique ceramide and filaggrin formulation rapidly improves chronic xerosis, pruritus, and quality of life in older adults.

Journal Article (Journal Article)

A skin care regimen which significantly improved atopic dermatitis and pruritus was evaluated for its efficacy and acceptability in senior subjects diagnosed with xerosis who also suffer from pruritus. This was an open-label, single-center study, designed to evaluate the daily use of a skin care regimen for 15 days. Assessments were made at baseline, day 8 and day 15 for visual skin dryness, transepidermal water loss (TEWL), hydration, desquamation, subject-perceived itch and quality of life (QoL). Twenty-five subjects, ages 60-73 years, had significantly improved skin visual dryness, hydration, desquamation, itch and QoL at days 8 and 15, relative to baseline (P < .05). TEWL was improved, though not significantly. Subjects expressed a high degree of satisfaction with the results. This regimen provides geriatric patients with an easily incorporated skin routine to help improve a common symptom of aging skin which negatively affects QoL.

Full Text

Duke Authors

Cited Authors

  • Chang, ALS; Chen, SC; Osterberg, L; Brandt, S; von Grote, EC; Meckfessel, MH

Published Date

  • January 2018

Published In

Volume / Issue

  • 39 / 1

Start / End Page

  • 24 - 28

PubMed ID

  • 28600081

Electronic International Standard Serial Number (EISSN)

  • 1528-3984

Digital Object Identifier (DOI)

  • 10.1016/j.gerinurse.2017.05.002

Language

  • eng

Conference Location

  • United States