BACKGROUND: Video-based patient education about long-term systemic corticosteroid treatment has not been assessed. OBJECTIVE: To compare video-based versus verbal education in patient knowledge gained and satisfaction. METHODS: English-speaking adults (≥18 years) were recruited from March-August 2013 from medical dermatology clinics. Study provider clinics were the unit of randomization. Verbal subjects heard a script based on the standard discussions of two top systemic corticosteroid prescribers at Emory. Video subjects viewed a video developed by the investigators. A 12-item survey created by the the investigators assessed baseline and post-education knowledge (immediate, one-, three-, and six-month). RESULTS: Baseline knowledge scores averaged 7.2±2.2 correct answers with no between-group differences. Post-education, the video group's (N=39) mean paired score difference was 0.9±2.0 higher than the verbal group's (p<0.04). After 1 month, most scores maintained gains with no between-group differences. 97% of patients in each group were satisfied (none were unsatisfied) with their education. LIMITATIONS: Our cohort was more literate than the general public, and a minority of subjects completed long-term follow up assessments. CONCLUSION: Video education enhanced near-term patient knowledge more than verbal education and maintained patient satisfaction.