RIPK3: Beyond Necroptosis.

Journal Article (Journal Article)

In this issue of Immunity, Daniels et al. (2019) demonstrate that RIPK3 signaling limits Zika virus (ZIKV) infection in the central nervous system independently of its function in necroptosis by promoting itaconate production in infected neurons, thereby revealing a neuron-specific mechanism of metabolite-mediated ZIKV control.

Full Text

Duke Authors

Cited Authors

  • Evans, AS; Coyne, CB

Published Date

  • January 15, 2019

Published In

Volume / Issue

  • 50 / 1

Start / End Page

  • 1 - 3

PubMed ID

  • 30650369

Electronic International Standard Serial Number (EISSN)

  • 1097-4180

Digital Object Identifier (DOI)

  • 10.1016/j.immuni.2018.12.031


  • eng

Conference Location

  • United States