A pilot quality-of-life instrument for acne rosacea.

Journal Article (Journal Article)

BACKGROUND: No rosacea-specific quality-of-life (QOL) instrument exists. OBJECTIVE: We sought to develop a validated, reliable rosacea-specific instrument. METHODS: From 6 in-depth interviews, we composed 21 rosacea-specific items. These items and Skindex-29 were administered in a validation cohort (n = 59). Internal consistency reliability and reproducibility were measured with Cronbach's coefficient alpha and intraclass correlation coefficient, respectively. Responsiveness was assessed comparing baseline with 4- to 6-month responses. Construct validity was assessed with principal axes factor analyses. Discriminant validity was examined with an additional 38 patients comparing differences in responsiveness between the rosacea-specific QOL instrument and Skindex. RESULTS: Reliability was high (Cronbach's alpha: 0.82-0.97, intraclass correlation coefficient: 0.70-0.95). The rosacea-specific QOL instrument showed preliminary responsiveness for patients with improved disease (P

Full Text

Duke Authors

Cited Authors

  • Nicholson, K; Abramova, L; Chren, M-M; Yeung, J; Chon, SY; Chen, SC

Published Date

  • August 2007

Published In

Volume / Issue

  • 57 / 2

Start / End Page

  • 213 - 221

PubMed ID

  • 17445948

Electronic International Standard Serial Number (EISSN)

  • 1097-6787

Digital Object Identifier (DOI)

  • 10.1016/j.jaad.2007.01.048


  • eng

Conference Location

  • United States