Ventricular septal rupture and cardiogenic shock complicating STEMI during COVID-19 pandemic: An old foe re-emerges.

Journal Article (Journal Article)

The COVID 19 pandemic resulted in a total reduction in the number of hospitalizations for acute coronary syndromes. A consequence of the delay in coronary revascularization has been the resurgence of structural complications of myocardial infarctions. Ventricular septal rupture (VSR) complicating late presenting acute myocardial infarction (AMI) is associated with high mortality despite advances in both surgical repair and perioperative management. Current data suggests a declining mortality with delay in VSR repair; however, these patients may develop cardiogenic shock while waiting for surgery. Available options are limited for patients with VSR who develop right ventricular failure and cardiogenic shock. The survival rate is very low in patients with cardiogenic shock undergoing surgical or percutaneous VSR repair. In this study we present two late presenting ST elevation MI patients who were complicated by rapidly declining hemodynamics and impending organ failure. Both patients were bridged with venoarterial extracorporeal membrane oxygenation (ECMO) to cardiac transplant.

Full Text

Duke Authors

Cited Authors

  • Bakhshi, H; Gattani, R; Ekanem, E; Singh, R; Desai, M; Speir, AM; Sinha, SS; Sherwood, MW; Tehrani, B; Batchelor, W

Published Date

  • March 2021

Published In

Volume / Issue

  • 50 / 2

Start / End Page

  • 292 - 295

PubMed ID

  • 33387761

Pubmed Central ID

  • PMC7756170

Electronic International Standard Serial Number (EISSN)

  • 1527-3288

Digital Object Identifier (DOI)

  • 10.1016/j.hrtlng.2020.12.013


  • eng

Conference Location

  • United States