Journal Article (Journal Article;Review)

Mucormycosis is a rare but aggressive fungal disease that mainly affects patients with poorly controlled diabetes mellitus and those who are severely immunocompromised, including patients with hematological malignancies and solid organ transplant recipients. Early recognition of infection is critical for treatment success, followed by prompt initiation of antifungal therapy with lipid formulation amphotericin B. Posaconazole and isavuconazole should be used for stepdown and salvage therapy. Surgical debridement is key for tissue diagnosis and treatment and should be pursued urgently whenever possible. In addition to surgery and antifungal therapy, reverting the underlying risk factor for infection is important for treatment response.

Full Text

Duke Authors

Cited Authors

  • Steinbrink, JM; Miceli, MH

Published Date

  • June 2021

Published In

Volume / Issue

  • 35 / 2

Start / End Page

  • 435 - 452

PubMed ID

  • 34016285

Electronic International Standard Serial Number (EISSN)

  • 1557-9824

Digital Object Identifier (DOI)

  • 10.1016/j.idc.2021.03.009


  • eng

Conference Location

  • United States