Mucormycosis.
Publication
, Journal Article
Steinbrink, JM; Miceli, MH
Published in: Infect Dis Clin North Am
June 2021
Mucormycosis is a rare but aggressive fungal disease that mainly affects patients with poorly controlled diabetes mellitus and those who are severely immunocompromised, including patients with hematological malignancies and solid organ transplant recipients. Early recognition of infection is critical for treatment success, followed by prompt initiation of antifungal therapy with lipid formulation amphotericin B. Posaconazole and isavuconazole should be used for stepdown and salvage therapy. Surgical debridement is key for tissue diagnosis and treatment and should be pursued urgently whenever possible. In addition to surgery and antifungal therapy, reverting the underlying risk factor for infection is important for treatment response.
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Published In
Infect Dis Clin North Am
DOI
EISSN
1557-9824
Publication Date
June 2021
Volume
35
Issue
2
Start / End Page
435 / 452
Location
United States
Related Subject Headings
- Mucormycosis
- Mucorales
- Microbiology
- Immunocompromised Host
- Humans
- Diabetes Mellitus, Type 2
- Antifungal Agents
- 4202 Epidemiology
- 3202 Clinical sciences
- 1117 Public Health and Health Services
Citation
APA
Chicago
ICMJE
MLA
NLM
Steinbrink, J. M., & Miceli, M. H. (2021). Mucormycosis. Infect Dis Clin North Am, 35(2), 435–452. https://doi.org/10.1016/j.idc.2021.03.009
Steinbrink, Julie M., and Marisa H. Miceli. “Mucormycosis.” Infect Dis Clin North Am 35, no. 2 (June 2021): 435–52. https://doi.org/10.1016/j.idc.2021.03.009.
Steinbrink JM, Miceli MH. Mucormycosis. Infect Dis Clin North Am. 2021 Jun;35(2):435–52.
Steinbrink, Julie M., and Marisa H. Miceli. “Mucormycosis.” Infect Dis Clin North Am, vol. 35, no. 2, June 2021, pp. 435–52. Pubmed, doi:10.1016/j.idc.2021.03.009.
Steinbrink JM, Miceli MH. Mucormycosis. Infect Dis Clin North Am. 2021 Jun;35(2):435–452.
Published In
Infect Dis Clin North Am
DOI
EISSN
1557-9824
Publication Date
June 2021
Volume
35
Issue
2
Start / End Page
435 / 452
Location
United States
Related Subject Headings
- Mucormycosis
- Mucorales
- Microbiology
- Immunocompromised Host
- Humans
- Diabetes Mellitus, Type 2
- Antifungal Agents
- 4202 Epidemiology
- 3202 Clinical sciences
- 1117 Public Health and Health Services