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FT-4202, an allosteric activator of pyruvate kinase-R, demonstrates proof of mechanism and proof of concept after multiple daily doses in a phase 1 study of patients with sickle cell disease

Publication ,  Conference
Brown, RC; Cruz, K; Kalfa, TA; Kuypers, FA; Saraf, SL; Estepp, JH; Smart, LR; Malik, P; Lerman, M; Mayer, R; Ribadeneira, MD; Forsyth, S ...
Published in: BRITISH JOURNAL OF HAEMATOLOGY
2021

Duke Scholars

Published In

BRITISH JOURNAL OF HAEMATOLOGY

EISSN

1365-2141

ISSN

0007-1048

Publication Date

2021

Volume

193

Start / End Page

23 / 24

Related Subject Headings

  • Immunology
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

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Brown, R. C., Cruz, K., Kalfa, T. A., Kuypers, F. A., Saraf, S. L., Estepp, J. H., … Telen, M. J. (2021). FT-4202, an allosteric activator of pyruvate kinase-R, demonstrates proof of mechanism and proof of concept after multiple daily doses in a phase 1 study of patients with sickle cell disease. In BRITISH JOURNAL OF HAEMATOLOGY (Vol. 193, pp. 23–24).
Brown, R Clark, Kimberly Cruz, Theodosia A. Kalfa, Frans A. Kuypers, Santosh L. Saraf, Jeremie H. Estepp, Luke R. Smart, et al. “FT-4202, an allosteric activator of pyruvate kinase-R, demonstrates proof of mechanism and proof of concept after multiple daily doses in a phase 1 study of patients with sickle cell disease.” In BRITISH JOURNAL OF HAEMATOLOGY, 193:23–24, 2021.
Brown RC, Cruz K, Kalfa TA, Kuypers FA, Saraf SL, Estepp JH, Smart LR, Malik P, Lerman M, Mayer R, Ribadeneira MD, Forsyth S, Schroeder P, Wu E, Kelly P, Telen MJ. FT-4202, an allosteric activator of pyruvate kinase-R, demonstrates proof of mechanism and proof of concept after multiple daily doses in a phase 1 study of patients with sickle cell disease. BRITISH JOURNAL OF HAEMATOLOGY. 2021. p. 23–24.
Journal cover image

Published In

BRITISH JOURNAL OF HAEMATOLOGY

EISSN

1365-2141

ISSN

0007-1048

Publication Date

2021

Volume

193

Start / End Page

23 / 24

Related Subject Headings

  • Immunology
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology