Skip to main content
Journal cover image

Guidelines for clinical trials of frontal fibrosing alopecia: consensus recommendations from the International FFA Cooperative Group (IFFACG).

Publication ,  Journal Article
Olsen, EA; Harries, M; Tosti, A; Bergfeld, W; Blume-Peytavi, U; Callender, V; Chasapi, V; Correia, O; Cotsarelis, G; Dhurat, R; Dlova, N ...
Published in: Br J Dermatol
December 2021

BACKGROUND: Frontal fibrosing alopecia (FFA) has become one of the most common causes of cicatricial alopecia worldwide. However, there is a lack of clear aetiology and robust clinical trial evidence for the efficacy and safety of agents currently used for treatment. OBJECTIVES: To enable data to be collected worldwide on FFA using common criteria and assessment methods. METHODS: A multicentre, international group of experts in hair loss was convened by email to create consensus recommendations for clinical trials. Consensus was defined at > 90% agreement on each recommended part of these guidelines. RESULTS: Standardized diagnostic criteria, severity rating, staging, and investigator and patient assessment of scalp hair loss and other clinical features of FFA were created. CONCLUSIONS: These guidelines should allow the collection of reliable aggregate data on FFA and advance efforts in both clinical and basic research to close knowledge gaps in this condition.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Br J Dermatol

DOI

EISSN

1365-2133

Publication Date

December 2021

Volume

185

Issue

6

Start / End Page

1221 / 1231

Location

England

Related Subject Headings

  • Scalp
  • Lichen Planus
  • Humans
  • Guidelines as Topic
  • Dermatology & Venereal Diseases
  • Consensus
  • Clinical Trials as Topic
  • Cicatrix
  • Alopecia
  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Olsen, E. A., Harries, M., Tosti, A., Bergfeld, W., Blume-Peytavi, U., Callender, V., … Vano-Galvan, S. (2021). Guidelines for clinical trials of frontal fibrosing alopecia: consensus recommendations from the International FFA Cooperative Group (IFFACG). Br J Dermatol, 185(6), 1221–1231. https://doi.org/10.1111/bjd.20567
Olsen, E. A., M. Harries, A. Tosti, W. Bergfeld, U. Blume-Peytavi, V. Callender, V. Chasapi, et al. “Guidelines for clinical trials of frontal fibrosing alopecia: consensus recommendations from the International FFA Cooperative Group (IFFACG).Br J Dermatol 185, no. 6 (December 2021): 1221–31. https://doi.org/10.1111/bjd.20567.
Olsen EA, Harries M, Tosti A, Bergfeld W, Blume-Peytavi U, Callender V, et al. Guidelines for clinical trials of frontal fibrosing alopecia: consensus recommendations from the International FFA Cooperative Group (IFFACG). Br J Dermatol. 2021 Dec;185(6):1221–31.
Olsen, E. A., et al. “Guidelines for clinical trials of frontal fibrosing alopecia: consensus recommendations from the International FFA Cooperative Group (IFFACG).Br J Dermatol, vol. 185, no. 6, Dec. 2021, pp. 1221–31. Pubmed, doi:10.1111/bjd.20567.
Olsen EA, Harries M, Tosti A, Bergfeld W, Blume-Peytavi U, Callender V, Chasapi V, Correia O, Cotsarelis G, Dhurat R, Dlova N, Doche I, Enechukwu N, Grimalt R, Itami S, Hordinsky M, Khobzei K, Lee W-S, Malakar S, Messenger A, McMichael A, Mirmirani P, Ovcharenko Y, Papanikou S, Pinto GM, Piraccini BM, Pirmez R, Reygagne P, Roberts J, Rudnicka L, Saceda-Corralo D, Shapiro J, Silyuk T, Sinclair R, Soares RO, Souissi A, Vogt A, Washenik K, Zlotogorski A, Canfield D, Vano-Galvan S. Guidelines for clinical trials of frontal fibrosing alopecia: consensus recommendations from the International FFA Cooperative Group (IFFACG). Br J Dermatol. 2021 Dec;185(6):1221–1231.
Journal cover image

Published In

Br J Dermatol

DOI

EISSN

1365-2133

Publication Date

December 2021

Volume

185

Issue

6

Start / End Page

1221 / 1231

Location

England

Related Subject Headings

  • Scalp
  • Lichen Planus
  • Humans
  • Guidelines as Topic
  • Dermatology & Venereal Diseases
  • Consensus
  • Clinical Trials as Topic
  • Cicatrix
  • Alopecia
  • 3202 Clinical sciences