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Harmonized outcome measures for use in degenerative lumbar spondylolisthesis patient registries and clinical practice.

Publication ,  Journal Article
Harbaugh, RE; Devin, C; Leavy, MB; Ghogawala, Z; Archer, KR; Bydon, M; Goertz, C; Dinstein, D; Nerenz, DR; Eakin, GS; Lavelle, W; Shaffer, WO ...
Published in: J Neurosurg Spine
March 19, 2021

OBJECTIVE: The development of new treatment approaches for degenerative lumbar spondylolisthesis (DLS) has introduced many questions about comparative effectiveness and long-term outcomes. Patient registries collect robust, longitudinal data that could be combined or aggregated to form a national and potentially international research data infrastructure to address these and other research questions. However, linking data across registries is challenging because registries typically define and capture different outcome measures. Variation in outcome measures occurs in clinical practice and other types of research studies as well, limiting the utility of existing data sources for addressing new research questions. The purpose of this project was to develop a minimum set of patient- and clinician-relevant standardized outcome measures that are feasible for collection in DLS registries and clinical practice. METHODS: Nineteen DLS registries, observational studies, and quality improvement efforts were invited to participate and submit outcome measures. A stakeholder panel was organized that included representatives from medical specialty societies, health systems, government agencies, payers, industries, health information technology organizations, and patient advocacy groups. The panel categorized the measures using the Agency for Healthcare Research and Quality's Outcome Measures Framework (OMF), identified a minimum set of outcome measures, and developed standardized definitions through a consensus-based process. RESULTS: The panel identified and harmonized 57 outcome measures into a minimum set of 10 core outcome measure areas and 6 supplemental outcome measure areas. The measures are organized into the OMF categories of survival, clinical response, events of interest, patient-reported outcomes, and resource utilization. CONCLUSIONS: This effort identified a minimum set of standardized measures that are relevant to patients and clinicians and appropriate for use in DLS registries, other research efforts, and clinical practice. Collection of these measures across registries and clinical practice is an important step for building research data infrastructure, creating learning healthcare systems, and improving patient management and outcomes in DLS.

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Published In

J Neurosurg Spine

DOI

EISSN

1547-5646

Publication Date

March 19, 2021

Volume

34

Issue

6

Start / End Page

888 / 896

Location

United States

Related Subject Headings

  • Orthopedics
  • 3209 Neurosciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Harbaugh, R. E., Devin, C., Leavy, M. B., Ghogawala, Z., Archer, K. R., Bydon, M., … Gliklich, R. E. (2021). Harmonized outcome measures for use in degenerative lumbar spondylolisthesis patient registries and clinical practice. J Neurosurg Spine, 34(6), 888–896. https://doi.org/10.3171/2020.9.SPINE20437
Harbaugh, Robert E., Clinton Devin, Michelle B. Leavy, Zoher Ghogawala, Kristin R. Archer, Mohamad Bydon, Christine Goertz, et al. “Harmonized outcome measures for use in degenerative lumbar spondylolisthesis patient registries and clinical practice.J Neurosurg Spine 34, no. 6 (March 19, 2021): 888–96. https://doi.org/10.3171/2020.9.SPINE20437.
Harbaugh RE, Devin C, Leavy MB, Ghogawala Z, Archer KR, Bydon M, et al. Harmonized outcome measures for use in degenerative lumbar spondylolisthesis patient registries and clinical practice. J Neurosurg Spine. 2021 Mar 19;34(6):888–96.
Harbaugh, Robert E., et al. “Harmonized outcome measures for use in degenerative lumbar spondylolisthesis patient registries and clinical practice.J Neurosurg Spine, vol. 34, no. 6, Mar. 2021, pp. 888–96. Pubmed, doi:10.3171/2020.9.SPINE20437.
Harbaugh RE, Devin C, Leavy MB, Ghogawala Z, Archer KR, Bydon M, Goertz C, Dinstein D, Nerenz DR, Eakin GS, Lavelle W, Shaffer WO, Arnold PM, Washabaugh CH, Gliklich RE. Harmonized outcome measures for use in degenerative lumbar spondylolisthesis patient registries and clinical practice. J Neurosurg Spine. 2021 Mar 19;34(6):888–896.

Published In

J Neurosurg Spine

DOI

EISSN

1547-5646

Publication Date

March 19, 2021

Volume

34

Issue

6

Start / End Page

888 / 896

Location

United States

Related Subject Headings

  • Orthopedics
  • 3209 Neurosciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences