Prostate Cancer Predisposition.

Journal Article (Journal Article;Review)

The identification and characterization of alterations in prostate cancer (PCa)-predisposing genes can help to inform screening strategies in undiagnosed men and treatment options in men in both the clinically localized and in the metastatic setting. This review provides an overview of the genetic basis underlying hereditary predisposition to PCa, the current role of genetics and PCa risk assessment, and how genetic risk factors affect aggressiveness and lethality of PCa.

Full Text

Duke Authors

Cited Authors

  • Bhanji, Y; Isaacs, WB; Xu, J; Cooney, KA

Published Date

  • August 2021

Published In

Volume / Issue

  • 48 / 3

Start / End Page

  • 283 - 296

PubMed ID

  • 34210485

Electronic International Standard Serial Number (EISSN)

  • 1558-318X

Digital Object Identifier (DOI)

  • 10.1016/j.ucl.2021.03.001


  • eng

Conference Location

  • United States