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Lymphatic Dysregulation in Patients With Heart Failure: JACC Review Topic of the Week.

Publication ,  Journal Article
Fudim, M; Salah, HM; Sathananthan, J; Bernier, M; Pabon-Ramos, W; Schwartz, RS; Rodés-Cabau, J; Côté, F; Khalifa, A; Virani, SA; Patel, MR
Published in: Journal of the American College of Cardiology
July 2021

The lymphatic system is an integral part of the circulatory system and plays an important role in the volume homeostasis of the human body. The complex anatomy and physiology paired with a lack of simple diagnostic tools to study the lymphatic system have led to an underappreciation of the contribution of the lymphatic system to acute and chronic heart failure (HF). Herein, we discuss the physiological role of the lymphatic system in volume management and the evidence demonstrating the dysregulation of the lymphatic system in HF. Further, we discuss the opportunity to target the lymphatic system in the management of HF and different potential approaches to accessing the lymphatic system.

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Published In

Journal of the American College of Cardiology

DOI

EISSN

1558-3597

ISSN

0735-1097

Publication Date

July 2021

Volume

78

Issue

1

Start / End Page

66 / 76

Related Subject Headings

  • Lymphatic System
  • Humans
  • Heart Failure
  • Fluid Shifts
  • Disease Management
  • Cardiovascular System & Hematology
  • 3201 Cardiovascular medicine and haematology
  • 1117 Public Health and Health Services
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

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Fudim, M., Salah, H. M., Sathananthan, J., Bernier, M., Pabon-Ramos, W., Schwartz, R. S., … Patel, M. R. (2021). Lymphatic Dysregulation in Patients With Heart Failure: JACC Review Topic of the Week. Journal of the American College of Cardiology, 78(1), 66–76. https://doi.org/10.1016/j.jacc.2021.04.090
Fudim, Marat, Husam M. Salah, Janarthanan Sathananthan, Mathieu Bernier, Waleska Pabon-Ramos, Robert S. Schwartz, Josep Rodés-Cabau, et al. “Lymphatic Dysregulation in Patients With Heart Failure: JACC Review Topic of the Week.Journal of the American College of Cardiology 78, no. 1 (July 2021): 66–76. https://doi.org/10.1016/j.jacc.2021.04.090.
Fudim M, Salah HM, Sathananthan J, Bernier M, Pabon-Ramos W, Schwartz RS, et al. Lymphatic Dysregulation in Patients With Heart Failure: JACC Review Topic of the Week. Journal of the American College of Cardiology. 2021 Jul;78(1):66–76.
Fudim, Marat, et al. “Lymphatic Dysregulation in Patients With Heart Failure: JACC Review Topic of the Week.Journal of the American College of Cardiology, vol. 78, no. 1, July 2021, pp. 66–76. Epmc, doi:10.1016/j.jacc.2021.04.090.
Fudim M, Salah HM, Sathananthan J, Bernier M, Pabon-Ramos W, Schwartz RS, Rodés-Cabau J, Côté F, Khalifa A, Virani SA, Patel MR. Lymphatic Dysregulation in Patients With Heart Failure: JACC Review Topic of the Week. Journal of the American College of Cardiology. 2021 Jul;78(1):66–76.
Journal cover image

Published In

Journal of the American College of Cardiology

DOI

EISSN

1558-3597

ISSN

0735-1097

Publication Date

July 2021

Volume

78

Issue

1

Start / End Page

66 / 76

Related Subject Headings

  • Lymphatic System
  • Humans
  • Heart Failure
  • Fluid Shifts
  • Disease Management
  • Cardiovascular System & Hematology
  • 3201 Cardiovascular medicine and haematology
  • 1117 Public Health and Health Services
  • 1102 Cardiorespiratory Medicine and Haematology