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Hypoventilation syndrome in neuromuscular disorders.

Publication ,  Journal Article
Wenninger, S; Jones, HN
Published in: Curr Opin Neurol
October 1, 2021

PURPOSE OF REVIEW: Hypoventilation syndrome in neuromuscular disorders (NMDs) is primarily due to respiratory muscle weakness and results in increased morbidity and mortality. This article highlights current aspects of neuromuscular hypoventilation syndrome, including pathophysiology, clinical symptoms, assessment, respiratory involvement in various NMD, and causal and symptomatic treatments with an emphasis on recent research and advances. RECENT FINDINGS AND SUMMARY: New therapeutic agents have been developed within the last years, proving a positive effect on respiratory system. Symptomatic therapies, including mechanical ventilation and cough assistance approaches, are important in NMD and respiratory muscle training may have benefit in strengthening respiratory muscles and should be offered patients with respiratory muscle weakness the same way as physiotherapy. Correct respiratory assessments and their correct interpretation are hallmarks for early diagnosis of hypoventilation syndrome and treatment.

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Published In

Curr Opin Neurol

DOI

EISSN

1473-6551

Publication Date

October 1, 2021

Volume

34

Issue

5

Start / End Page

686 / 696

Location

England

Related Subject Headings

  • Respiratory Muscles
  • Respiration, Artificial
  • Neuromuscular Diseases
  • Neurology & Neurosurgery
  • Muscle Weakness
  • Hypoventilation
  • Humans
  • 3209 Neurosciences
  • 3202 Clinical sciences
  • 1702 Cognitive Sciences
 

Citation

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Wenninger, S., & Jones, H. N. (2021). Hypoventilation syndrome in neuromuscular disorders. Curr Opin Neurol, 34(5), 686–696. https://doi.org/10.1097/WCO.0000000000000973
Wenninger, Stephan, and Harrison N. Jones. “Hypoventilation syndrome in neuromuscular disorders.Curr Opin Neurol 34, no. 5 (October 1, 2021): 686–96. https://doi.org/10.1097/WCO.0000000000000973.
Wenninger S, Jones HN. Hypoventilation syndrome in neuromuscular disorders. Curr Opin Neurol. 2021 Oct 1;34(5):686–96.
Wenninger, Stephan, and Harrison N. Jones. “Hypoventilation syndrome in neuromuscular disorders.Curr Opin Neurol, vol. 34, no. 5, Oct. 2021, pp. 686–96. Pubmed, doi:10.1097/WCO.0000000000000973.
Wenninger S, Jones HN. Hypoventilation syndrome in neuromuscular disorders. Curr Opin Neurol. 2021 Oct 1;34(5):686–696.

Published In

Curr Opin Neurol

DOI

EISSN

1473-6551

Publication Date

October 1, 2021

Volume

34

Issue

5

Start / End Page

686 / 696

Location

England

Related Subject Headings

  • Respiratory Muscles
  • Respiration, Artificial
  • Neuromuscular Diseases
  • Neurology & Neurosurgery
  • Muscle Weakness
  • Hypoventilation
  • Humans
  • 3209 Neurosciences
  • 3202 Clinical sciences
  • 1702 Cognitive Sciences