Blood product transfusion and lung transplant outcomes: A systematic review.

Journal Article (Journal Article;Review;Systematic Review)

The perioperative transfusion of blood products has long been linked to development of acute lung injury and associated with mortality across both medical and surgical patient populations.1,2 The need for blood product transfusion during and after lung transplantation is common and, in many instances, unavoidable. However, this practice may potentially be modifiable.3 In this systematic review, we explore and summarize what is known regarding the impact of blood product transfusion on outcomes following lung transplantation, highlighting the most recent work in this area. Overall, the majority of the literature consists of single center retrospective analyses or the work of multicenter working groups referencing the same database. In the end, there are a number of remaining questions regarding blood product transfusion and their downstream effects on graft function and survival.

Full Text

Duke Authors

Cited Authors

  • Klapper, JA; Hicks, AC; Ledbetter, L; Poisson, J; Hartwig, MG; Hashmi, N; Welsby, I; Bottiger, BA

Published Date

  • October 2021

Published In

Volume / Issue

  • 35 / 10

Start / End Page

  • e14404 -

PubMed ID

  • 34176163

Electronic International Standard Serial Number (EISSN)

  • 1399-0012

Digital Object Identifier (DOI)

  • 10.1111/ctr.14404


  • eng

Conference Location

  • Denmark