Longitudinal study of serpiginous choroiditis and serpiginous like choroiditis using wide field OCT angiography.
PURPOSE: To assess the ability of wide field Swept Source OCTA (SS-OCTA) imaging to detect morphological variations in Serpiginous Choroiditis (SC) and Serpiginous Like Choroiditis (SLC) in response to treatment and also analyze these findings quantitatively using Image J software. METHODS: Retrospective observational case series of nine eyes with clinical diagnosis of active SC and SLC, who underwent SS-OCTA and fundus autofluorescence (FAF) imaging at baseline and each follow up visit till 6 months. Morphological analysis was done by two independent graders and quantitative analysis to measure the size and intensity of lesion was done using publicly available Image J software at baseline and each follow up visit. DESIGN: Retrospective observational case series. RESULTS: Using SS-OCTA, all the active lesions followed a characteristic healing pattern. Active lesions appear well defined hypo flow void patches and as healing progressed, lesion became more ill-defined and iso-hyper- intense. Significant increase in mean intensity of the lesion could be apparent after 1 and 6 month of treatment. There was reduction in the size of lesions during follow up however this difference was not statistically significant. CONCLUSION: SS-OCTA could be a useful noninvasive tool to study the treatment response in SC/SLC both morphologically as well as quantitatively. Quantitative parameters need to be designed in further research studies to aid in uniform management and follow up of uveitis cases.
Duke Scholars
Published In
DOI
EISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- White Dot Syndromes
- Tuberculosis, Ocular
- Tomography, Optical Coherence
- Retrospective Studies
- Ophthalmology & Optometry
- Longitudinal Studies
- Humans
- Fluorescein Angiography
- Choroiditis
- Choroid
Citation
Published In
DOI
EISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- White Dot Syndromes
- Tuberculosis, Ocular
- Tomography, Optical Coherence
- Retrospective Studies
- Ophthalmology & Optometry
- Longitudinal Studies
- Humans
- Fluorescein Angiography
- Choroiditis
- Choroid