Surgical Management of Colorectal Cancer Liver Metastases.

Journal Article (Review;Journal Article)

Approximately 50% of colorectal cancer patients develop liver metastases. Hepatic metastases represent the most common cause of colorectal cancer-related mortality. Metastasectomy, if possible, represents the most effective treatment strategy; 20% of patients will be cured and more than 50% survive at least 5 years. Nuances to treatment planning hinge on whether patients present with resectable disease upfront, whether the future liver remnant is adequate, and whether the primary tumor, if present, is colon versus rectal in origin. This article discusses considerations impacting our approach to patients with colorectal liver metastases and the role for various multimodal treatment options.

Full Text

Duke Authors

Cited Authors

  • Padmanabhan, C; Nussbaum, DP; D'Angelica, M

Published Date

  • January 2021

Published In

Volume / Issue

  • 30 / 1

Start / End Page

  • 1 - 25

PubMed ID

  • 33220799

Electronic International Standard Serial Number (EISSN)

  • 1558-5042

International Standard Serial Number (ISSN)

  • 1055-3207

Digital Object Identifier (DOI)

  • 10.1016/j.soc.2020.09.002


  • eng