Remdesivir for the Prevention of Invasive Mechanical Ventilation or Death in Coronavirus Disease 2019 (COVID-19): A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-1 Cohort Data.
Publication
, Journal Article
Paules, CI; Gallagher, SK; Rapaka, RR; Davey, RT; Doernberg, SB; Grossberg, R; Hynes, NA; Ponce, PO; Short, WR; Voell, J; Wang, J; Yang, OO ...
Published in: Clin Infect Dis
April 9, 2022
This post hoc analysis of the Adaptive Coronavirus Disease 2019 (COVID-19) Treatment Trial-1 (ACTT-1) shows a treatment effect of remdesivir (RDV) on progression to invasive mechanical ventilation (IMV) or death. Additionally, we create a risk profile that better predicts progression than baseline oxygen requirement alone. The highest risk group derives the greatest treatment effect from RDV.
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Published In
Clin Infect Dis
DOI
EISSN
1537-6591
Publication Date
April 9, 2022
Volume
74
Issue
7
Start / End Page
1260 / 1264
Location
United States
Related Subject Headings
- SARS-CoV-2
- Respiration, Artificial
- Microbiology
- Humans
- Clinical Trials as Topic
- COVID-19 Drug Treatment
- Antiviral Agents
- Alanine
- Adenosine Monophosphate
- 3202 Clinical sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Paules, C. I., Gallagher, S. K., Rapaka, R. R., Davey, R. T., Doernberg, S. B., Grossberg, R., … Benson, C. A. (2022). Remdesivir for the Prevention of Invasive Mechanical Ventilation or Death in Coronavirus Disease 2019 (COVID-19): A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-1 Cohort Data. Clin Infect Dis, 74(7), 1260–1264. https://doi.org/10.1093/cid/ciab695
Paules, Catharine I., Shannon K. Gallagher, Rekha R. Rapaka, Richard T. Davey, Sarah B. Doernberg, Robert Grossberg, Noreen A. Hynes, et al. “Remdesivir for the Prevention of Invasive Mechanical Ventilation or Death in Coronavirus Disease 2019 (COVID-19): A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-1 Cohort Data.” Clin Infect Dis 74, no. 7 (April 9, 2022): 1260–64. https://doi.org/10.1093/cid/ciab695.
Paules CI, Gallagher SK, Rapaka RR, Davey RT, Doernberg SB, Grossberg R, et al. Remdesivir for the Prevention of Invasive Mechanical Ventilation or Death in Coronavirus Disease 2019 (COVID-19): A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-1 Cohort Data. Clin Infect Dis. 2022 Apr 9;74(7):1260–4.
Paules, Catharine I., et al. “Remdesivir for the Prevention of Invasive Mechanical Ventilation or Death in Coronavirus Disease 2019 (COVID-19): A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-1 Cohort Data.” Clin Infect Dis, vol. 74, no. 7, Apr. 2022, pp. 1260–64. Pubmed, doi:10.1093/cid/ciab695.
Paules CI, Gallagher SK, Rapaka RR, Davey RT, Doernberg SB, Grossberg R, Hynes NA, Ponce PO, Short WR, Voell J, Wang J, Yang OO, Wolfe CR, Lye DC, Dodd LE, Benson CA. Remdesivir for the Prevention of Invasive Mechanical Ventilation or Death in Coronavirus Disease 2019 (COVID-19): A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-1 Cohort Data. Clin Infect Dis. 2022 Apr 9;74(7):1260–1264.
Published In
Clin Infect Dis
DOI
EISSN
1537-6591
Publication Date
April 9, 2022
Volume
74
Issue
7
Start / End Page
1260 / 1264
Location
United States
Related Subject Headings
- SARS-CoV-2
- Respiration, Artificial
- Microbiology
- Humans
- Clinical Trials as Topic
- COVID-19 Drug Treatment
- Antiviral Agents
- Alanine
- Adenosine Monophosphate
- 3202 Clinical sciences