Diagnostic work-up for severe aplastic anemia in children: Consensus of the North American Pediatric Aplastic Anemia Consortium.

Journal Article (Journal Article)

The North American Pediatric Aplastic Anemia Consortium (NAPAAC) is a group of pediatric hematologist-oncologists, hematopathologists, and bone marrow transplant physicians from 46 institutions in North America with interest and expertise in aplastic anemia, inherited bone marrow failure syndromes, and myelodysplastic syndromes. The NAPAAC Bone Marrow Failure Diagnosis and Care Guidelines Working Group was established with the charge of harmonizing the approach to the diagnostic workup of aplastic anemia in an effort to standardize best practices in the field. This document outlines the rationale for initial evaluations in pediatric patients presenting with signs and symptoms concerning for severe aplastic anemia.

Full Text

Duke Authors

Cited Authors

  • Shimano, KA; Narla, A; Rose, MJ; Gloude, NJ; Allen, SW; Bergstrom, K; Broglie, L; Carella, BA; Castillo, P; de Jong, JLO; Dror, Y; Geddis, AE; Huang, JN; Lau, BW; McGuinn, C; Nakano, TA; Overholt, K; Rothman, JA; Sharathkumar, A; Shereck, E; Vlachos, A; Olson, TS; Bertuch, AA; Wlodarski, MW; Shimamura, A; Boklan, J

Published Date

  • November 1, 2021

Published In

Volume / Issue

  • 96 / 11

Start / End Page

  • 1491 - 1504

PubMed ID

  • 34342889

Electronic International Standard Serial Number (EISSN)

  • 1096-8652

Digital Object Identifier (DOI)

  • 10.1002/ajh.26310


  • eng

Conference Location

  • United States