Patterning small-molecule biocapture surfaces: microcontact insertion printing vs. photolithography.

Journal Article (Journal Article)

Chemical patterns prepared by self-assembly, combined with soft lithography or photolithography, are directly compared. Pattern fidelity can be controlled in both cases but patterning at the low densities necessary for small-molecule probe capture of large biomolecule targets is better accomplished using microcontact insertion printing (μCIP). Surfaces patterned by μCIP are used to capture biomolecule binding partners for the small molecules dopamine and biotin.

Full Text

Duke Authors

Cited Authors

  • Shuster, MJ; Vaish, A; Cao, HH; Guttentag, AI; McManigle, JE; Gibb, AL; Martinez-Rivera, M; Nezarati, RM; Hinds, JM; Liao, W-S; Weiss, PS; Andrews, AM

Published Date

  • October 14, 2011

Published In

Volume / Issue

  • 47 / 38

Start / End Page

  • 10641 - 10643

PubMed ID

  • 21874174

Electronic International Standard Serial Number (EISSN)

  • 1364-548X

Digital Object Identifier (DOI)

  • 10.1039/c1cc13002a


  • eng

Conference Location

  • England