Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation.

Journal Article (Journal Article)

Tens of thousands of patients with advanced lung diseases may be eligible to be considered as potential candidates for lung transplant around the world each year. The timing of referral, evaluation, determination of candidacy, and listing of candidates continues to pose challenges and even ethical dilemmas. To address these challenges, the International Society for Heart and Lung Transplantation appointed an international group of members to review the literature, to consider recent advances in the management of advanced lung diseases, and to update prior consensus documents on the selection of lung transplant candidates. The purpose of this updated consensus document is to assist providers throughout the world who are caring for patients with pulmonary disease to identify potential candidates for lung transplant, to optimize the timing of the referral of these patients to lung transplant centers, and to provide transplant centers with a framework for evaluating and selecting candidates. In addition to addressing general considerations and providing disease specific recommendations for referral and listing, this updated consensus document includes an ethical framework, a recognition of the variability in acceptance of risk between transplant centers, and establishes a system to account for how a combination of risk factors may be taken into consideration in candidate selection for lung transplantation.

Full Text

Duke Authors

Cited Authors

  • Leard, LE; Holm, AM; Valapour, M; Glanville, AR; Attawar, S; Aversa, M; Campos, SV; Christon, LM; Cypel, M; Dellgren, G; Hartwig, MG; Kapnadak, SG; Kolaitis, NA; Kotloff, RM; Patterson, CM; Shlobin, OA; Smith, PJ; Solé, A; Solomon, M; Weill, D; Wijsenbeek, MS; Willemse, BWM; Arcasoy, SM; Ramos, KJ

Published Date

  • November 2021

Published In

Volume / Issue

  • 40 / 11

Start / End Page

  • 1349 - 1379

PubMed ID

  • 34419372

Pubmed Central ID

  • PMC8979471

Electronic International Standard Serial Number (EISSN)

  • 1557-3117

Digital Object Identifier (DOI)

  • 10.1016/j.healun.2021.07.005


  • eng

Conference Location

  • United States