ISHLT consensus document on lung transplantation in patients with connective tissue disease: Part I: Epidemiology, assessment of extrapulmonary conditions, candidate evaluation, selection criteria, and pathology statements.

Journal Article (Journal Article)

Patients with connective tissue disease (CTD) and advanced lung disease are often considered suboptimal candidates for lung transplantation (LTx) due to their underlying medical complexity and potential surgical risk. There is substantial variability across LTx centers regarding the evaluation and listing of these patients. The International Society for Heart and Lung Transplantation-supported consensus document on lung transplantation in patients with CTD standardization aims to clarify definitions of each disease state included under the term CTD, to describe the extrapulmonary manifestations of each disease requiring consideration before transplantation, and to outline the absolute contraindications to transplantation allowing risk stratification during the evaluation and selection of candidates for LTx.

Full Text

Duke Authors

Cited Authors

  • Crespo, MM; Lease, ED; Sole, A; Sandorfi, N; Snyder, LD; Berry, GJ; Pavec, JL; Venado, AE; Cifrian, JM; Goldberg, H; Dilling, DF; Gries, C; Nair, A; Willie, K; Meyer, KC; Shah, RJ; Tokman, S; Holm, A; Patterson, CM; McWilliams, T; Shtraichman, O; Bemiss, B; Salgado, J; Farver, C; Strah, H; Wassilew, K; Kaza, V; Howsare, M; Murray, M; Bhorade, S; Budev, M

Published Date

  • November 2021

Published In

Volume / Issue

  • 40 / 11

Start / End Page

  • 1251 - 1266

PubMed ID

  • 34417111

Electronic International Standard Serial Number (EISSN)

  • 1557-3117

Digital Object Identifier (DOI)

  • 10.1016/j.healun.2021.07.014


  • eng

Conference Location

  • United States