Clinical and Technical Considerations for Brain PET Imaging for Dementia.

Journal Article (Review;Journal Article)

The number of cases of dementia has dramatically increased over the last decade. Imaging of the brain with PET has been used for many years, but in the past decade the radiopharmaceuticals and technology available for imaging dementia have vastly improved. In recent years, the U.S. Food and Drug Administration has approved 3 PET radiopharmaceuticals for detecting amyloid in brain, and tau PET radiopharmaceuticals are being investigated in clinical trials for use in dementia imaging. This paper will discuss different forms of dementia that can be imaged with PET, review common radiopharmaceuticals used for imaging dementia, and provide technical recommendations for performing the studies.

Full Text

Duke Authors

Cited Authors

  • Acuff, SN; Mathotaarachchi, S; Zukotynski, K; Osborne, D; Subramaniam, R; Alzheimer’s Disease Neuroimaging Initiative,

Published Date

  • March 2020

Published In

Volume / Issue

  • 48 / 1

Start / End Page

  • 5 - 8

PubMed ID

  • 31182663

Electronic International Standard Serial Number (EISSN)

  • 1535-5675

International Standard Serial Number (ISSN)

  • 0091-4916

Digital Object Identifier (DOI)

  • 10.2967/jnmt.118.220087


  • eng