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Clinical and Technical Considerations for Brain PET Imaging for Dementia.

Publication ,  Journal Article
Acuff, SN; Mathotaarachchi, S; Zukotynski, K; Osborne, D; Subramaniam, R; Alzheimer’s Disease Neuroimaging Initiative,
Published in: J Nucl Med Technol
March 2020

The number of cases of dementia has dramatically increased over the last decade. Imaging of the brain with PET has been used for many years, but in the past decade the radiopharmaceuticals and technology available for imaging dementia have vastly improved. In recent years, the U.S. Food and Drug Administration has approved 3 PET radiopharmaceuticals for detecting amyloid in brain, and tau PET radiopharmaceuticals are being investigated in clinical trials for use in dementia imaging. This paper will discuss different forms of dementia that can be imaged with PET, review common radiopharmaceuticals used for imaging dementia, and provide technical recommendations for performing the studies.

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Published In

J Nucl Med Technol

DOI

EISSN

1535-5675

Publication Date

March 2020

Volume

48

Issue

1

Start / End Page

5 / 8

Location

United States

Related Subject Headings

  • United States Food and Drug Administration
  • United States
  • Radiopharmaceuticals
  • Positron Emission Tomography Computed Tomography
  • Nuclear Medicine & Medical Imaging
  • Humans
  • Guidelines as Topic
  • Fluorodeoxyglucose F18
  • Drug Approval
  • Dementia
 

Citation

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Acuff, S. N., Mathotaarachchi, S., Zukotynski, K., Osborne, D., Subramaniam, R., & Alzheimer’s Disease Neuroimaging Initiative, . (2020). Clinical and Technical Considerations for Brain PET Imaging for Dementia. J Nucl Med Technol, 48(1), 5–8. https://doi.org/10.2967/jnmt.118.220087
Acuff, Shelley N., Sulantha Mathotaarachchi, Katherine Zukotynski, Dustin Osborne, Rathan Subramaniam, and Rathan Alzheimer’s Disease Neuroimaging Initiative. “Clinical and Technical Considerations for Brain PET Imaging for Dementia.J Nucl Med Technol 48, no. 1 (March 2020): 5–8. https://doi.org/10.2967/jnmt.118.220087.
Acuff SN, Mathotaarachchi S, Zukotynski K, Osborne D, Subramaniam R, Alzheimer’s Disease Neuroimaging Initiative. Clinical and Technical Considerations for Brain PET Imaging for Dementia. J Nucl Med Technol. 2020 Mar;48(1):5–8.
Acuff, Shelley N., et al. “Clinical and Technical Considerations for Brain PET Imaging for Dementia.J Nucl Med Technol, vol. 48, no. 1, Mar. 2020, pp. 5–8. Pubmed, doi:10.2967/jnmt.118.220087.
Acuff SN, Mathotaarachchi S, Zukotynski K, Osborne D, Subramaniam R, Alzheimer’s Disease Neuroimaging Initiative. Clinical and Technical Considerations for Brain PET Imaging for Dementia. J Nucl Med Technol. 2020 Mar;48(1):5–8.

Published In

J Nucl Med Technol

DOI

EISSN

1535-5675

Publication Date

March 2020

Volume

48

Issue

1

Start / End Page

5 / 8

Location

United States

Related Subject Headings

  • United States Food and Drug Administration
  • United States
  • Radiopharmaceuticals
  • Positron Emission Tomography Computed Tomography
  • Nuclear Medicine & Medical Imaging
  • Humans
  • Guidelines as Topic
  • Fluorodeoxyglucose F18
  • Drug Approval
  • Dementia