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PET/Computed Tomography and Precision Medicine: Musculoskeletal Sarcoma.

Publication ,  Journal Article
Kandathil, A; Subramaniam, RM
Published in: PET Clin
October 2017

Skeletal and soft tissue sarcomas need early and accurate diagnosis, staging, and treatment for optimal outcome. 18F-FDG PET/computed tomography (CT) is indicated in staging of patients with high-grade sarcomas and acts as a surrogate marker of histopathologic grade, guiding biopsy to most aggressive portion of the tumor. Pretherapy and posttherapy 18F-FDG PET/CT metabolic parameters are reliable indicators of survival in patients with sarcoma with an important role in posttreatment response assessment, enabling the treatment plan to be modified in nonresponders. 18F-FDG PET/CT is particularly useful in the evaluation of molecular targeted therapies, which induce metabolic change before structural change.

Duke Scholars

Published In

PET Clin

DOI

EISSN

1879-9809

Publication Date

October 2017

Volume

12

Issue

4

Start / End Page

475 / 488

Location

United States

Related Subject Headings

  • Sarcoma
  • Radiopharmaceuticals
  • Precision Medicine
  • Positron Emission Tomography Computed Tomography
  • Nuclear Medicine & Medical Imaging
  • Muscle Neoplasms
  • Humans
  • Fluorodeoxyglucose F18
  • Bone Neoplasms
  • 3211 Oncology and carcinogenesis
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Kandathil, A., & Subramaniam, R. M. (2017). PET/Computed Tomography and Precision Medicine: Musculoskeletal Sarcoma. PET Clin, 12(4), 475–488. https://doi.org/10.1016/j.cpet.2017.05.005
Kandathil, Asha, and Rathan M. Subramaniam. “PET/Computed Tomography and Precision Medicine: Musculoskeletal Sarcoma.PET Clin 12, no. 4 (October 2017): 475–88. https://doi.org/10.1016/j.cpet.2017.05.005.
Kandathil A, Subramaniam RM. PET/Computed Tomography and Precision Medicine: Musculoskeletal Sarcoma. PET Clin. 2017 Oct;12(4):475–88.
Kandathil, Asha, and Rathan M. Subramaniam. “PET/Computed Tomography and Precision Medicine: Musculoskeletal Sarcoma.PET Clin, vol. 12, no. 4, Oct. 2017, pp. 475–88. Pubmed, doi:10.1016/j.cpet.2017.05.005.
Kandathil A, Subramaniam RM. PET/Computed Tomography and Precision Medicine: Musculoskeletal Sarcoma. PET Clin. 2017 Oct;12(4):475–488.
Journal cover image

Published In

PET Clin

DOI

EISSN

1879-9809

Publication Date

October 2017

Volume

12

Issue

4

Start / End Page

475 / 488

Location

United States

Related Subject Headings

  • Sarcoma
  • Radiopharmaceuticals
  • Precision Medicine
  • Positron Emission Tomography Computed Tomography
  • Nuclear Medicine & Medical Imaging
  • Muscle Neoplasms
  • Humans
  • Fluorodeoxyglucose F18
  • Bone Neoplasms
  • 3211 Oncology and carcinogenesis