PET-Computed Tomography and Precision Medicine in Pancreatic Adenocarcinoma and Pancreatic Neuroendocrine Tumors.

Journal Article (Journal Article;Review)

18F-FDG PET/CT has been described as an accurate tool for initial diagnosis of pancreatic adenocarcinoma. It differentiates benign from malignant causes; detects local and, especially, distant spread of disease; and is a very good predictor of patient prognosis. Pancreatic neuroendocrine tumors are rare tumors that originate from the islet cells of the pancreas. Currently, 68Ga-DOTA-labeled somatostatin analogs are considered the best modality for detection of well-differentiated neuroendocrine tumors. 18F-FDG PET/CT has a role in patients with poorly differentiated tumors. Recent studies have demonstrated improved survival in patients with metastatic neuroendocrine tumors treated with radiolabeled somatostatin analogs.

Full Text

Duke Authors

Cited Authors

  • Pinho, DF; Subramaniam, RM

Published Date

  • October 2017

Published In

Volume / Issue

  • 12 / 4

Start / End Page

  • 407 - 421

PubMed ID

  • 28867112

Electronic International Standard Serial Number (EISSN)

  • 1879-9809

Digital Object Identifier (DOI)

  • 10.1016/j.cpet.2017.05.003


  • eng

Conference Location

  • United States