Molecular Imaging and Precision Medicine in Head and Neck Cancer.
Publication
, Journal Article
Mena, E; Thippsandra, S; Yanamadala, A; Redy, S; Pattanayak, P; Subramaniam, RM
Published in: PET Clin
January 2017
The concept of using tumor genomic profiling information has revolutionized personalized cancer treatment. Head and neck (HN) cancer management is being influenced by recent discoveries of activating mutations in epidermal growth factor receptor and related targeted therapies with tyrosine kinase inhibitors, targeted therapies for Kristen Rat Sarcoma, and MET proto-oncogenes. Molecular imaging using PET plays an important role in assessing the biologic behavior of HN cancer with the goal of delivering individualized cancer treatment. This review summarizes recent genomic discoveries in HN cancer and their implications for functional PET imaging in assessing response to targeted therapies, and drug resistance mechanisms.
Duke Scholars
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Published In
PET Clin
DOI
EISSN
1879-9809
Publication Date
January 2017
Volume
12
Issue
1
Start / End Page
7 / 25
Location
United States
Related Subject Headings
- Radiopharmaceuticals
- Prognosis
- Precision Medicine
- Positron-Emission Tomography
- Positron Emission Tomography Computed Tomography
- Nuclear Medicine & Medical Imaging
- Molecular Targeted Therapy
- Molecular Imaging
- Humans
- Head and Neck Neoplasms
Citation
APA
Chicago
ICMJE
MLA
NLM
Mena, E., Thippsandra, S., Yanamadala, A., Redy, S., Pattanayak, P., & Subramaniam, R. M. (2017). Molecular Imaging and Precision Medicine in Head and Neck Cancer. PET Clin, 12(1), 7–25. https://doi.org/10.1016/j.cpet.2016.08.009
Mena, Esther, Shwetha Thippsandra, Anusha Yanamadala, Siddaling Redy, Puskar Pattanayak, and Rathan M. Subramaniam. “Molecular Imaging and Precision Medicine in Head and Neck Cancer.” PET Clin 12, no. 1 (January 2017): 7–25. https://doi.org/10.1016/j.cpet.2016.08.009.
Mena E, Thippsandra S, Yanamadala A, Redy S, Pattanayak P, Subramaniam RM. Molecular Imaging and Precision Medicine in Head and Neck Cancer. PET Clin. 2017 Jan;12(1):7–25.
Mena, Esther, et al. “Molecular Imaging and Precision Medicine in Head and Neck Cancer.” PET Clin, vol. 12, no. 1, Jan. 2017, pp. 7–25. Pubmed, doi:10.1016/j.cpet.2016.08.009.
Mena E, Thippsandra S, Yanamadala A, Redy S, Pattanayak P, Subramaniam RM. Molecular Imaging and Precision Medicine in Head and Neck Cancer. PET Clin. 2017 Jan;12(1):7–25.
Published In
PET Clin
DOI
EISSN
1879-9809
Publication Date
January 2017
Volume
12
Issue
1
Start / End Page
7 / 25
Location
United States
Related Subject Headings
- Radiopharmaceuticals
- Prognosis
- Precision Medicine
- Positron-Emission Tomography
- Positron Emission Tomography Computed Tomography
- Nuclear Medicine & Medical Imaging
- Molecular Targeted Therapy
- Molecular Imaging
- Humans
- Head and Neck Neoplasms