Methods and challenges in quantitative imaging biomarker development.

Journal Article (Journal Article;Review)

Academic radiology is poised to play an important role in the development and implementation of quantitative imaging (QI) tools. This article, drafted by the Association of University Radiologists Radiology Research Alliance Quantitative Imaging Task Force, reviews current issues in QI biomarker research. We discuss motivations for advancing QI, define key terms, present a framework for QI biomarker research, and outline challenges in QI biomarker development. We conclude by describing where QI research and development is currently taking place and discussing the paramount role of academic radiology in this rapidly evolving field.

Full Text

Duke Authors

Cited Authors

  • Abramson, RG; Burton, KR; Yu, J-PJ; Scalzetti, EM; Yankeelov, TE; Rosenkrantz, AB; Mendiratta-Lala, M; Bartholmai, BJ; Ganeshan, D; Lenchik, L; Subramaniam, RM

Published Date

  • January 2015

Published In

Volume / Issue

  • 22 / 1

Start / End Page

  • 25 - 32

PubMed ID

  • 25481515

Pubmed Central ID

  • PMC4258641

Electronic International Standard Serial Number (EISSN)

  • 1878-4046

Digital Object Identifier (DOI)

  • 10.1016/j.acra.2014.09.001


  • eng

Conference Location

  • United States